The chaperone SmgGDS-607 has a dual role, both activating and inhibiting farnesylation of small GTPases.
                第一作者:
                
                        
Desirée,García-Torres
                        
                
            
            
                第一单位:
                
                        
                            Program in Chemical Biology, University of Michigan, Ann Arbor, Michigan 48109.
                            
                        
                
            
                    
                作者:
                
                
            
            
        
			主题词
			烷基和芳基转移酶类(Alkyl and Aryl Transferases);氨基酸特征结构(Amino Acid Motifs);生物催化(Biocatalysis);GTP磷酸水解酶类(GTP Phosphohydrolases);鸟嘌呤核苷酸交换因子类(Guanine Nucleotide Exchange Factors);人类(Humans);动力学(Kinetics);单体GTP结合蛋白质类(Monomeric GTP-Binding Proteins);诱变, 定点(Mutagenesis, Site-Directed);蛋白质结合(Protein Binding);蛋白质异戊烯化(Protein Prenylation);原癌基因蛋白质类p21(ras)(Proto-Oncogene Proteins p21(ras));重组蛋白质类(Recombinant Proteins);底物特异性(Substrate Specificity);热力学(Thermodynamics);肿瘤抑制蛋白质类(Tumor Suppressor Proteins)
		
        		
			DOI
			10.1074/jbc.RA119.007438
		
        		
			PMID
			31197034
		
        		
			发布时间
			2021-02-05
		
    - 浏览2
 
                
            The Journal of biological chemistry
11793-11804页
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