Cruzain structures: apocruzain and cruzain bound to S-methyl thiomethanesulfonate and implications for drug design.

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作者： Elany,Barbosa da Silva ^[1] ; Elfriede,Dall ^[2] ; Peter,Briza ^[2] ; Hans,Brandstetter ^[2] ; Rafaela Salgado,Ferreira ^[1]

作者单位： Laboratório de Modelagem Molecular e Planejamento de Fármacos, Departamento de Bioquímica e Imunologia, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil. ^[1] Department of Biosciences, University of Salzburg, Salzburg, Austria. ^[2]

关键词 Chagas disease MMTS Trypanosoma cruzi cruzain

主题词脱辅蛋白质类(Apoproteins);结晶学, X线(Crystallography, X-Ray);半胱氨酸内肽酶类(Cysteine Endopeptidases);半胱氨酸蛋白酶抑制剂(Cysteine Proteinase Inhibitors);药物设计(Drug Design);甲磺酸甲酯(Methyl Methanesulfonate);模型, 分子(Models, Molecular);蛋白质构象(Protein Conformation);原虫蛋白质类(Protozoan Proteins)

DOI 10.1107/S2053230X19006320

PMID 31204688

发布时间 2024-07-17

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Acta crystallographica. Section F, Structural biology communications

2019年75卷Pt 6期

419-427页

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Cruzain structures: apocruzain and cruzain bound to S-methyl thiomethanesulfonate and implications for drug design.

Acta crystallographica. Section F, Structural biology communications

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Acta crystallographica. Section F, Structural biology communications

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Cruzain structures: apocruzain and cruzain bound to S-methyl thiomethanesulfonate and implications for drug design.

Acta crystallographica. Section F, Structural biology communications

相似文献

Acta crystallographica. Section F, Structural biology communications

相关期刊

检索历史清除