Anthraquinones from Cassiae semen as thrombin inhibitors: in vitro and in silico studies.

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第一作者： Xiao,Yu

第一单位： Department of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital of Zhengzhou University; Henan Key Laboratory of Digestive Organ Transplantation; Zhengzhou Key Laboratory of Hepatobiliary & Pancreatic Diseases and Organ Transplantation; Open and Key Laboratory of Hepatobiliary & Pancreatic Surgery and Digestive Organ Transplantation at Henan Universities; Zhengzhou, 450001, China.

作者： Xiao,Yu ^[1] ; Ling-Hua,Wei ^[1] ; Jia-Kai,Zhang ^[1] ; Tian-Ran,Chen ^[1] ; Qiang,Jin ^[2] ; Yi-Nan,Wang ^[2] ; Shui-Jun,Zhang ^[1] ; Tong-Yi,Dou ^[3] ; Yun-Feng,Cao ^[4] ; Wen-Zhi,Guo ^[5] ; Guang-Bo,Ge ^[6] ; Ling,Yang ^[2]

作者单位： Department of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital of Zhengzhou University; Henan Key Laboratory of Digestive Organ Transplantation; Zhengzhou Key Laboratory of Hepatobiliary & Pancreatic Diseases and Organ Transplantation; Open and Key Laboratory of Hepatobiliary & Pancreatic Surgery and Digestive Organ Transplantation at Henan Universities; Zhengzhou, 450001, China. ^[1] Institute of Interdisciplinary Integrative Medicine Research, Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, China. ^[2] School of Life Science and Medicine, Dalian University of Technology, Panjin, 124221, China. ^[3] Dalian Runsheng Kangtai Medical Laboratory Co.Ltd, Dalian, China. ^[4] Department of Hepatobiliary and Pancreatic Surgery, The First Affiliated Hospital of Zhengzhou University; Henan Key Laboratory of Digestive Organ Transplantation; Zhengzhou Key Laboratory of Hepatobiliary & Pancreatic Diseases and Organ Transplantation; Open and Key Laboratory of Hepatobiliary & Pancreatic Surgery and Digestive Organ Transplantation at Henan Universities; Zhengzhou, 450001, China. Electronic address: guowz66@163.com. ^[5] Institute of Interdisciplinary Integrative Medicine Research, Shanghai University of Traditional Chinese Medicine, Shanghai, 201203, China. Electronic address: geguangbo@dicp.ac.cn. ^[6]

关键词 Aurantio-obtusin Cassia obtusifolia L.Cassiae semen Obtusifolin Thrombin inhibitor