首页> Journal of bone and mineral metabolism> Angiopoietin-like 2 upregulation promotes human chondrocyte injury via NF-κB and p38/MAPK signaling pathway.

Angiopoietin-like 2 upregulation promotes human chondrocyte injury via NF-κB and p38/MAPK signaling pathway.

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第一作者： Wenshan,Shan

第一单位： Department of Orthopaedics, The First Affiliated Hospital of Anhui Medical University, 218#Ji Xi Road, Hefei, 230032, Anhui, China.

作者： Wenshan,Shan ^[1] ; Chao,Cheng ^[2] ; Wei,Huang ^[3] ; Zhenfei,Ding ^[1] ; Sha,Luo ^[4] ; Guanjun,Cui ^[1] ; Wei,Lu ^[1] ; Fuen,Liu ^[1] ; JieGou,Xu ^[5] ; Wei,He ^[6] ; Zongsheng,Yin ^[7]

作者单位： Department of Orthopaedics, The First Affiliated Hospital of Anhui Medical University, 218#Ji Xi Road, Hefei, 230032, Anhui, China. ^[1] Department of Orthopaedics, The Fourth Affiliated Hospital of Anhui Medical University, 372#Tun Xi Road, Hefei, 230032, Anhui, China. ^[2] Department of Orthopaedics, The First Affiliated Hospital of Anhui Medical University, 218#Ji Xi Road, Hefei, 230032, Anhui, China.;Division of Life Sciences and Medicine, Department of Orthopaedics, The First Affiliated Hospital of USTC, University of Science and Technology of China, 17#Lu Jiang Road, Hefei, 230001, Anhui, China. ^[3] School of Basic Medical Science, and the First Clinical Medical College, Anhui Medical University, 81# Mei Shan Road, Hefei, 230032, Anhui, China. ^[4] School of Basic Medical Science, and the First Clinical Medical College, Anhui Medical University, 81# Mei Shan Road, Hefei, 230032, Anhui, China. xujiegou@ahmu.edu.cn. ^[5] School of Basic Medical Science, and the First Clinical Medical College, Anhui Medical University, 81# Mei Shan Road, Hefei, 230032, Anhui, China. weihe@ahmu.edu.cn. ^[6] Department of Orthopaedics, The First Affiliated Hospital of Anhui Medical University, 218#Ji Xi Road, Hefei, 230032, Anhui, China. anhuiyzs@126.com. ^[7]

关键词 ANGPTL2 ECM degradation Inflammation mediators production Osteoarthritis