首页> Current topics in medicinal chemistry> 5-Nitro-Thiophene-Thiosemicarbazone Derivatives Present Antitumor Activity Mediated by Apoptosis and DNA Intercalation.

5-Nitro-Thiophene-Thiosemicarbazone Derivatives Present Antitumor Activity Mediated by Apoptosis and DNA Intercalation.

导出原文传递

翻译打印收藏纠错

第一作者： Karla Mirella,Roque Marques

第一单位： Bioactive Products Prospecting Laboratory, Department of Antibiotics, Federal University of Pernambuco, Recife-PE, Brazil.

作者： Karla Mirella,Roque Marques ^[1] ; Maria Rodrigues,do Desterro ^[1] ; Sandrine Maria,de Arruda ^[1] ; Luiz Nascimento,de Araújo Neto ^[2] ; Maria,do Carmo Alves de Lima ^[2] ; Sinara Mônica Vitalino,de Almeida ^[3] ; Edjan Carlos Dantas,da Silva ^[4] ; Thiago Mendonça,de Aquino ^[4] ; Edeildo Ferreira,da Silva-Júnior ^[4] ; João Xavier,de Araújo-Júnior ^[4] ; Marina,de M Silva ^[5] ; Maria Dayanne,de A Dantas ^[5] ; Josué Carinhanha C,Santos ^[5] ; Isis M,Figueiredo ^[5] ; Marc-Antoine,Bazin ^[6] ; Pascal,Marchand ^[6] ; Teresinha Gonçalves,da Silva ^[1] ; Francisco Jaime Bezerra,Mendonça Junior ^[7]

作者单位： Bioactive Products Prospecting Laboratory, Department of Antibiotics, Federal University of Pernambuco, Recife-PE, Brazil. ^[1] Laboratory of Chemistry and Therapeutic Innovation, Department of Antibiotics, Federal University of Pernambuco, Recife-PE, Brazil. ^[2] Laboratory of Molecular Biology, University of Pernambuco, Garanhuns-PE, Brazil. ^[3] Laboratory of Medicinal Chemistry, Nursing and Pharmacy School, Federal University of Alagoas, Maceio-AL, Brazil. ^[4] Laboratory of Development and Instrumentation in Analytical Chemistry, Institute of Chemistry and Biotechnology, Federal University of Alagoas, Maceio-AL, Brazil. ^[5] Universite de Nantes, Cibles et medicaments des infections et du cancer, IICiMed, EA1155, F-44000 Nantes, France. ^[6] Laboratory of Synthesis and Drug Delivery, Department of Biological Sciences, State University of Paraiba, Joao Pessoa-PB, Brazil. ^[7]

关键词 Antitumor activity Apoptosis Cancer DNA Intercalation Thiophene Thiosemicarbazone.