Star-shaped poly(2-aminoethyl methacrylate)s as non-viral gene carriers: Exploring structure-function relationship.

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作者： Wenjuan,Chen ^[1] ; Yanhang,Hong ^[1] ; Tao,Zhang ^[2] ; Deling,Kong ^[3] ; Mingming,Zhang ^[4] ; Qiqing,Zhang ^[5] ; Chun,Wang ^[6]

作者单位： Tianjin Key Laboratory of Biomedical Materials, Institute of Biomedical Engineering, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300192, PR China. ^[1] School of Pharmacy, Tianjin Medical University, Tianjin 300070, PR China. ^[2] Tianjin Key Laboratory of Biomedical Materials, Institute of Biomedical Engineering, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300192, PR China; State Key Laboratory of Medicinal Chemical Biology, Key Laboratory of Bioactive Materials, Ministry of Education, College of Life Sciences, Nankai University, Tianjin 300071, PR China. ^[3] Tianjin Key Laboratory of Biomedical Materials, Institute of Biomedical Engineering, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300192, PR China. Electronic address: zhangmm@bme.cams.cn. ^[4] Tianjin Key Laboratory of Biomedical Materials, Institute of Biomedical Engineering, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300192, PR China. Electronic address: zhangqiq@126.com. ^[5] Department of Biomedical Engineering, University of Minnesota, 7-105 Hasselmo Hall, 312 Church Street S. E., Minneapolis, MN 55455, USA. Electronic address: wangx504@umn.edu. ^[6]

关键词 Gene transfection Poly(2-aminoethyl methacrylate) (PAEM)Star-shaped polycation Structure-function relationship