Indirect Radioiodination of DARPin G3 Using N-succinimidyl-<i>Para</i>-Iodobenzoate Improves the Contrast of HER2 Molecular Imaging.

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作者： Anzhelika,Vorobyeva ^[1] ; Alexey,Schulga ^[2] ; Sara S,Rinne ^[3] ; Tyran,Günther ^[4] ; Anna,Orlova ^[5] ; Sergey,Deyev ^[6] ; Vladimir,Tolmachev ^[7]

作者单位： Department of Immunology, Genetics and Pathology, Uppsala University, 75185 Uppsala, Sweden. anzhelika.vorobyeva@igp.uu.se. ^[1] Molecular Immunology Laboratory, Shemyakin & Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia. schulga@gmail.com. ^[2] Department of Medicinal Chemistry, Uppsala University, 75123 Uppsala, Sweden. sara.rinne@pet.medchem.uu.se. ^[3] Department of Immunology, Genetics and Pathology, Uppsala University, 75185 Uppsala, Sweden. tyrangunther@gmail.com. ^[4] Department of Medicinal Chemistry, Uppsala University, 75123 Uppsala, Sweden. anna.orlova@ilk.uu.se. ^[5] Science for Life Laboratory, Uppsala University, 75123 Uppsala, Sweden. anna.orlova@ilk.uu.se. ^[6] Molecular Immunology Laboratory, Shemyakin & Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia. deyev@ibch.ru. ^[7] Bio-Nanophotonic Lab, Institute of Engineering Physics for Biomedicine (PhysBio), National Research Nuclear University 'MEPhI', 115409 Moscow, Russia. deyev@ibch.ru. ^[8] Nuclear Medicine Department, Cancer Research Institute, Tomsk National Research Medical Center Russian Academy of Sciences, 634050 Tomsk, Russia. deyev@ibch.ru. ^[9] Department of Immunology, Genetics and Pathology, Uppsala University, 75185 Uppsala, Sweden. vladimir.tolmachev@igp.uu.se. ^[10]

关键词 DARPin HER2 imaging iodine radioiodination radionuclide