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首页> British journal of pharmacology> Salinomycin exerts anti-colorectal cancer activity by targeting the β-catenin/T-cell factor complex.

Salinomycin exerts anti-colorectal cancer activity by targeting the β-catenin/T-cell factor complex.

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作者： Zhongyuan,Wang ^[1] ; Liang,Zhou ^[1] ; Yanpeng,Xiong ^[1] ; Shubin,Yu ^[1] ; Huan,Li ^[1] ; Jiaoyang,Fan ^[1] ; Fan,Li ^[2] ; Zijie,Su ^[1] ; Jiaxing,Song ^[1] ; Qi,Sun ^[1] ; Shan-Shan,Liu ^[1] ; Yuqing,Xia ^[1] ; Liang,Zhao ^[1] ; Shiyue,Li ^[1] ; Fang,Guo ^[3] ; Peng,Huang ^[2] ; Dennis A,Carson ^[4] ; Desheng,Lu ^[1]

作者单位： Guangdong Key Laboratory for Genome Stability & Disease Prevention, Carson International Cancer Center, Department of Pharmacology, Shenzhen University Health Science Center, Shenzhen, China. ^[1] Guangdong Key Laboratory for Biomedical Measurements and Ultrasound Imaging, Laboratory of Evolutionary Theranostics, School of Biomedical Engineering, Shenzhen University Health Science Center, Shenzhen, China. ^[2] Center for Systems Biomedicine, Shanghai Jiao Tong University, Shanghai, China. ^[3] Guangdong Key Laboratory for Genome Stability & Disease Prevention, Carson International Cancer Center, Department of Pharmacology, Shenzhen University Health Science Center, Shenzhen, China.;Moores Cancer Center, University of California San Diego (UCSD), La Jolla, California. ^[4]

主题词动物(Animals);抗肿瘤药(Antineoplastic Agents);细胞增殖(Cell Proliferation);细胞, 培养的(Cells, Cultured);结直肠肿瘤(Colorectal Neoplasms);剂量效应关系, 药物(Dose-Response Relationship, Drug);药物筛选试验, 抗肿瘤(Drug Screening Assays, Antitumor);HEK293细胞(HEK293 Cells);人类(Humans);男(雄)性(Male);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);肿瘤, 实验性(Neoplasms, Experimental);吡喃类(Pyrans);信号传导(Signal Transduction);构效关系(Structure-Activity Relationship);TCF转录因子类(TCF Transcription Factors);β连环素(beta Catenin)

DOI 10.1111/bph.14770

PMID 31236922

发布时间 2024-07-19

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准确一般字义偏差语意偏离译文作用小提交

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British journal of pharmacology

British journal of pharmacology

2019年176卷17期

3390-3406页

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