Salinomycin exerts anti-colorectal cancer activity by targeting the β-catenin/T-cell factor complex.
第一作者:
Zhongyuan,Wang
第一单位:
Guangdong Key Laboratory for Genome Stability & Disease Prevention, Carson International Cancer Center, Department of Pharmacology, Shenzhen University Health Science Center, Shenzhen, China.
作者:
医学主题词
动物(Animals);抗肿瘤药(Antineoplastic Agents);细胞增殖(Cell Proliferation);细胞, 培养的(Cells, Cultured);结直肠肿瘤(Colorectal Neoplasms);剂量效应关系, 药物(Dose-Response Relationship, Drug);药物筛选试验, 抗肿瘤(Drug Screening Assays, Antitumor);HEK293细胞(HEK293 Cells);人类(Humans);男(雄)性(Male);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);肿瘤, 实验性(Neoplasms, Experimental);吡喃类(Pyrans);信号传导(Signal Transduction);构效关系(Structure-Activity Relationship);TCF转录因子类(TCF Transcription Factors);β连环素(beta Catenin)
DOI
10.1111/bph.14770
PMID
31236922
发布时间
2024-07-19
- 浏览3
British journal of pharmacology
3390-3406页
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