Integrative genomic analysis of matched primary and metastatic pediatric osteosarcoma.

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作者： Gian Luca,Negri ^[1] ; Bruno M,Grande ^[2] ; Alberto,Delaidelli ^[3] ; Amal,El-Naggar ^[1] ; Dawn,Cochrane ^[4] ; Ching C,Lau ^[1] ; Timothy J,Triche ^[5] ; Richard A,Moore ^[1] ; Steven Jm,Jones ^[6] ; Alexandre,Montpetit ^[7] ; Marco A,Marra ^[8] ; David,Malkin ^[2] ; Ryan D,Morin ^[2] ; Poul H,Sorensen ^[9]

作者单位： Department of Molecular Oncology, British Columbia Cancer Agency, Vancouver, Canada. ^[1] Canada's Michael Smith Genome Sciences Centre, BC Cancer, Vancouver, Canada. ^[2] Department of Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, Canada. ^[3] Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, Canada. ^[4] Department of Pathology, Faculty of Medicine, Menoufia University, Shebeen El-Kom, Egypt. ^[5] Texas Children's Cancer and Hematology Centers, Department of Pediatrics, Baylor College of Medicine and Texas Children's Hospital, Houston, TX, USA. ^[6] Department of Pathology and Laboratory Medicine, Childrens Hospital Los Angeles, Los Angeles, CA, USA. ^[7] Department of Pathology, Keck School of Medicine of USC, Los Angeles, CA, USA. ^[8] Department of Human Genetics, McGill University and Research Institute, McGill University Health Centre, Montreal, Canada. ^[9] Department of Medical Genetics, University of British Columbia, Vancouver, Canada. ^[10] Division of Haematology-Oncology, The Hospital for Sick Children, Department of Pediatrics, University of Toronto, Toronto, Canada. ^[11]

关键词 KDR VEGF childhood bone sarcomas genome sequencing metastasis osteosarcoma