Spermidine/spermine-N<sup>1</sup>-acetyltransferase ablation impacts tauopathy-induced polyamine stress response.

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作者： Leslie A,Sandusky-Beltran ^[1] ; Andrii,Kovalenko ^[2] ; Chao,Ma ^[1] ; John Ivan T,Calahatian ^[3] ; Devon S,Placides ^[1] ; Mallory D,Watler ^[1] ; Jerry B,Hunt ^[1] ; April L,Darling ^[1] ; Jeremy D,Baker ^[4] ; Laura J,Blair ^[4] ; Mackenzie D,Martin ^[4] ; Sarah N,Fontaine ^[4] ; Chad A,Dickey ^[4] ; April L,Lussier ^[4] ; Edwin J,Weeber ^[3] ; Maj-Linda B,Selenica ^[3] ; Kevin R,Nash ^[1] ; Marcia N,Gordon ^[3] ; Dave,Morgan ^[3] ; Daniel C,Lee ^[5]

作者单位： Byrd Alzheimer's Institute, Department of Pharmaceutical Sciences, University of South Florida, 4001 E. Fletcher Ave, Tampa, FL, 33613, USA. ^[1] Neuroscience Institute, Department of Neuroscience and Physiology, New York University School of Medicine, 1 Park Avenue, New York, NY, 10016, USA. ^[2] Byrd Alzheimer's Institute, Department of Molecular Pharmacology and Physiology, University of South Florida, Tampa, FL, 33613, USA. ^[3] Byrd Alzheimer's Institute, Department of Molecular Medicine, University of South Florida, Tampa, FL, 33613, USA. ^[4] Department of Translational Science & Molecular Medicine, Michigan State University, 400 Monroe Ave NW, Grand Rapids, MI, 49503, USA. ^[5] Byrd Alzheimer's Institute, Department of Pharmaceutical Sciences, University of South Florida, 4001 E. Fletcher Ave, Tampa, FL, 33613, USA. dlee1@health.usf.edu. ^[6]

关键词 Alzheimer’s disease Hippocampus Polyamine dysregulation Tau