Personalized Drug Sensitivity Screening for Bladder Cancer Using Conditionally Reprogrammed Patient-derived Cells.

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第一作者： Kimmo,Kettunen

第一单位： Institute of Biomedicine, University of Turku, and Department of Pathology, Turku University Hospital, Turku, Finland.

作者： Kimmo,Kettunen ^[1] ; Peter J,Boström ^[2] ; Tarja,Lamminen ^[3] ; Taija,Heinosalo ^[4] ; Gun,West ^[1] ; Irena,Saarinen ^[1] ; Katja,Kaipio ^[3] ; Juha,Rantala ^[5] ; Chris,Albanese ^[6] ; Matti,Poutanen ^[4] ; Pekka,Taimen ^[7]

作者单位： Institute of Biomedicine, University of Turku, and Department of Pathology, Turku University Hospital, Turku, Finland. ^[1] Department of Urology, Turku University Hospital and University of Turku, Turku, Finland. ^[2] Institute of Biomedicine, University of Turku, and Department of Pathology, Turku University Hospital, Turku, Finland; Department of Urology, Turku University Hospital and University of Turku, Turku, Finland. ^[3] Institute of Biomedicine, Research Center for Integrative Physiology and Pharmacology and Turku Center for Disease Modeling, University of Turku, Turku, Finland. ^[4] Misvik Biology, Turku, Finland. ^[5] Departments of Oncology and Pathology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, USA. ^[6] Institute of Biomedicine, University of Turku, and Department of Pathology, Turku University Hospital, Turku, Finland. Electronic address: pekka.taimen@utu.fi. ^[7]

关键词 Bladder cancer Chemotherapy Conditional reprogramming Drug sensitivity testing Patient-derived cultures Small cell carcinoma

主题词抗肿瘤药(Antineoplastic Agents);药物筛选试验, 抗肿瘤(Drug Screening Assays, Antitumor);人类(Humans);肿瘤细胞, 培养的(Tumor Cells, Cultured);膀胱肿瘤(Urinary Bladder Neoplasms)

DOI 10.1016/j.eururo.2019.06.016

PMID 31256944

发布时间 2022-02-04

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