Untargeted Metabolite Mapping in 3D Cell Culture Models Using High Spectral Resolution FT-ICR Mass Spectrometry Imaging.

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作者： Lulu H,Tucker ^[1] ; Gregory R,Hamm ^[2] ; Rebecca J E,Sargeant ^[2] ; Richard J A,Goodwin ^[2] ; C Logan,Mackay ^[1] ; Colin J,Campbell ^[1] ; David J,Clarke ^[1]

作者单位： EaStCHEM School of Chemistry , University of Edinburgh , Edinburgh EH9 3FJ , United Kingdom. ^[1] Pathology, Clinical Pharmacology and Safety Sciences, BioPharmaceuticals R&D , AstraZeneca , Cambridge CB4 0WG , United Kingdom. ^[2]

主题词回旋加速器(Cyclotrons);傅里叶分析(Fourier Analysis);人类(Humans);代谢组学(Metabolomics);球形体, 细胞(Spheroids, Cellular);肿瘤微环境(Tumor Microenvironment)

DOI 10.1021/acs.analchem.9b00661

PMID 31265253

发布时间 2020-09-21

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