换一批GSTZ1-1 Deficiency Activates NRF2/IGF1R Axis in HCC via Accumulation of Oncometabolite Succinylacetone.
第一作者：
Fan,Yang
第一单位：
Key Laboratory of Molecular Biology for Infectious Diseases (Ministry of Education), Department of Infectious Diseases, The Second Affiliated Hospital, Institute for Viral Hepatitis, Chongqing Medical University, Chongqing, China.;Department of Infectious Diseases, The First Affiliated Hospital, Chongqing Medical University, Chongqing, China.
作者：
医学主题词
动物(Animals);癌, 肝细胞(Carcinoma, Hepatocellular);细胞系, 肿瘤(Cell Line, Tumor);细胞增殖(Cell Proliferation);二乙基亚硝胺(Diethylnitrosamine);减量调节(Down-Regulation);女(雌)性(Female);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);基因敲低技术(Gene Knockdown Techniques);谷胱甘肽转移酶(Glutathione Transferase);Hep G2细胞(Hep G2 Cells);庚酸盐类(Heptanoates);人类(Humans);肝肿瘤(Liver Neoplasms);男(雄)性(Male);小鼠(Mice);NF-E2相关因子2(NF-E2-Related Factor 2);肿瘤, 实验性(Neoplasms, Experimental);预后(Prognosis);受体, IGF1型(Receptor, IGF Type 1);信号传导(Signal Transduction);存活率分析(Survival Analysis)
DOI
10.15252/embj.2019101964
PMID
31267557
发布时间
2021-01-10
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The EMBO journal
e101964页
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