Mechanisms of Resistance to EGFR Inhibition Reveal Metabolic Vulnerabilities in Human GBM.

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第一作者： Andrew,McKinney

第一单位： Department of Neurological Surgery, Brain Tumor Center, University of California, San Francisco, San Francisco, California.

作者： Andrew,McKinney ^[1] ; Olle R,Lindberg ^[1] ; Jane R,Engler ^[1] ; Katharine Y,Chen ^[1] ; Anupam,Kumar ^[1] ; Henry,Gong ^[1] ; Kan V,Lu ^[1] ; Erin F,Simonds ^[1] ; Timothy F,Cloughesy ^[2] ; Linda M,Liau ^[3] ; Michael,Prados ^[4] ; Andrew W,Bollen ^[3] ; Mitchel S,Berger ^[5] ; Joseph T C,Shieh ^[1] ; C David,James ^[6] ; Theodore P,Nicolaides ^[1] ; William H,Yong ^[7] ; Albert,Lai ^[8] ; Monika E,Hegi ^[9] ; William A,Weiss ^[1] ; Joanna J,Phillips ^[10]

作者单位： Department of Neurological Surgery, Brain Tumor Center, University of California, San Francisco, San Francisco, California. ^[1] Department of Neurology, University of California, San Francisco, San Francisco, California. ^[2] UCLA Neuro-Oncology Program, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California. ^[3] Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California. ^[4] Department of Neurosurgery, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California. ^[5] Department of Pathology, Division of Neuropathology, University of California, San Francisco, San Francisco, California. ^[6] Division of Medical Genetics, Department of Pediatrics, UCSF Benioff Children's Hospital, University of California, San Francisco, San Francisco, California. ^[7] Institute for Human Genetics, University of California, San Francisco, San Francisco, California. ^[8] Neurological Surgery, Feinberg School of Medicine, Northwestern University, Chicago, Illinois. ^[9] Department of Pediatrics, UCSF Benioff Children's Hospital, University of California, San Francisco, San Francisco, California. ^[10] Department of Pathology and Laboratory Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, California. ^[11] Neuroscience Research Center and Service of Neurosurgery, Lausanne University Hospital and University of Lausanne, Lausanne, Switzerland. ^[12] Department of Neurological Surgery, Brain Tumor Center, University of California, San Francisco, San Francisco, California. Joanna.phillips@ucsf.edu. ^[13]