Blockade of STAT3 Causes Severe In Vitro and In Vivo Maturation Defects in Intestinal Organoids Derived from Human Embryonic Stem Cells.

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第一作者： Kwang Bo,Jung

第一单位： Stem Cell Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon 34141, Korea.

作者： Kwang Bo,Jung ^[1] ; Ohman,Kwon ^[2] ; Mi-Ok,Lee ^[1] ; Hana,Lee ^[1] ; Ye Seul,Son ^[1] ; Omer,Habib ^[2] ; Jung-Hwa,Oh ^[1] ; Hyun-Soo,Cho ^[2] ; Cho-Rok,Jung ^[3] ; Janghwan,Kim ^[4] ; Mi-Young,Son ^[1]

作者单位： Stem Cell Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon 34141, Korea. ^[1] Department of Functional Genomics, KRIBB School of Bioscience, Korea University of Science and Technology, Daejeon 34113, Korea. ^[2] Department of Pathology, College of Medicine, Kyung Hee University, Seoul 02447, Korea. ^[3] Department of predictive toxicology, Korea Institute of Toxicology, Daejeon 34114, Korea. ^[4] Stem Cell Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon 34141, Korea. crjung@kribb.re.kr. ^[5] Department of Functional Genomics, KRIBB School of Bioscience, Korea University of Science and Technology, Daejeon 34113, Korea. crjung@kribb.re.kr. ^[6] Stem Cell Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon 34141, Korea. janghwan.kim@kribb.re.kr. ^[7] Department of Functional Genomics, KRIBB School of Bioscience, Korea University of Science and Technology, Daejeon 34113, Korea. janghwan.kim@kribb.re.kr. ^[8] Stem Cell Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon 34141, Korea. myson@kribb.re.kr. ^[9] Department of Functional Genomics, KRIBB School of Bioscience, Korea University of Science and Technology, Daejeon 34113, Korea. myson@kribb.re.kr. ^[10]

关键词 CRISPR/Cas9 STAT3 human embryonic stem cell human intestinal organoid in vitro maturation

DOI 10.3390/jcm8070976

PMID 31277507

发布时间 2020-09-30

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Journal of clinical medicine

2019年8卷7期

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Blockade of STAT3 Causes Severe In Vitro and In Vivo Maturation Defects in Intestinal Organoids Derived from Human Embryonic Stem Cells.

Journal of clinical medicine

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Journal of clinical medicine

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Blockade of STAT3 Causes Severe In Vitro and In Vivo Maturation Defects in Intestinal Organoids Derived from Human Embryonic Stem Cells.

Journal of clinical medicine

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Journal of clinical medicine

相关期刊

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