Prevalence of Suspected Hereditary Cancer Syndromes and Germline Mutations Among a Diverse Cohort of Probands Reporting a Family History of Prostate Cancer: Toward Informing Cascade Testing for Men.

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作者： Thenappan,Chandrasekar ^[1] ; Laura,Gross ^[2] ; Leonard G,Gomella ^[3] ; Sarah E,Hegarty ^[4] ; Joon Yau,Leong ^[3] ; Veda N,Giri ^[5]

作者单位： Department of Urology, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA, USA. Electronic address: thenappan.chandrasekar@gmail.com. ^[1] Cancer Risk Assessment and Clinical Cancer Genetics, Division of Population Science, Department of Medical Oncology, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA, USA. ^[2] Department of Urology, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA, USA. ^[3] Division of Biostatistics, Department of Pharmacology and Experimental Therapeutics, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, USA. ^[4] Department of Urology, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA, USA; Cancer Risk Assessment and Clinical Cancer Genetics, Division of Population Science, Department of Medical Oncology, Sidney Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA, USA. ^[5]

关键词 BRCA1 BRCA2 Genetic testing Hereditary breast and ovarian cancer Hereditary cancer syndrome Lynch syndrome Prostate cancer

主题词女(雌)性(Female);基因检测(Genetic Testing);生殖细胞系突变(Germ-Line Mutation);人类(Humans);男(雄)性(Male);肿瘤综合征, 遗传性(Neoplastic Syndromes, Hereditary);系谱(Pedigree);患病率(Prevalence);前瞻性研究(Prospective Studies);前列腺肿瘤(Prostatic Neoplasms)

DOI 10.1016/j.euo.2019.06.010

PMID 31278035

发布时间 2021-05-31

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European urology oncology

2020年3卷3期

291-297页

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Prevalence of Suspected Hereditary Cancer Syndromes and Germline Mutations Among a Diverse Cohort of Probands Reporting a Family History of Prostate Cancer: Toward Informing Cascade Testing for Men.

European urology oncology

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Prevalence of Suspected Hereditary Cancer Syndromes and Germline Mutations Among a Diverse Cohort of Probands Reporting a Family History of Prostate Cancer: Toward Informing Cascade Testing for Men.

European urology oncology

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European urology oncology

相关期刊

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