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Metformin induces lipogenic differentiation in myofibroblasts to reverse lung fibrosis.

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作者单位: Key Laboratory of Interventional Pulmonology of Zhejiang Province, Department of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Wenzhou Medical University, 325035, Wenzhou, China. [1] Cardio-Pulmonary Institute (CPI) and Department of Pulmonary and Critical Care Medicine and Infectious Diseases, Universities of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), Justus-Liebig University Giessen, 35392, Giessen, Germany. [2] Ludwig Boltzmann Institute for Lung Vascular Research, Otto Loewi Research Center, Medical University Graz, 8010, Graz, Austria. [3] International Collaborative Center on Growth Factor Research and School of Pharmaceutical Sciences, Wenzhou Medical University, 325035, Wenzhou, China. [4] Institut de Pharmacologie Moleculaire et Cellulaire (IPMC), Centre National de la Recherche Scientifique (CNRS), UMR 7275, Sophia Antipolis, 06560, Valbonne, France. [5] Universite Cote d'Azur, 06108, Nice, France. [6] Key Laboratory of Interventional Pulmonology of Zhejiang Province, Department of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Wenzhou Medical University, 325035, Wenzhou, China. saverio.bellusci@innere.med.uni-giessen.de. [7] Cardio-Pulmonary Institute (CPI) and Department of Pulmonary and Critical Care Medicine and Infectious Diseases, Universities of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), Justus-Liebig University Giessen, 35392, Giessen, Germany. saverio.bellusci@innere.med.uni-giessen.de. [8] International Collaborative Center on Growth Factor Research and School of Pharmaceutical Sciences, Wenzhou Medical University, 325035, Wenzhou, China. saverio.bellusci@innere.med.uni-giessen.de. [9] Key Laboratory of Interventional Pulmonology of Zhejiang Province, Department of Pulmonary and Critical Care Medicine, The First Affiliated Hospital of Wenzhou Medical University, 325035, Wenzhou, China. elie.el-agha@innere.med.uni-giessen.de. [10] Cardio-Pulmonary Institute (CPI) and Department of Pulmonary and Critical Care Medicine and Infectious Diseases, Universities of Giessen and Marburg Lung Center (UGMLC), Member of the German Center for Lung Research (DZL), Justus-Liebig University Giessen, 35392, Giessen, Germany. elie.el-agha@innere.med.uni-giessen.de. [11] International Collaborative Center on Growth Factor Research and School of Pharmaceutical Sciences, Wenzhou Medical University, 325035, Wenzhou, China. elie.el-agha@innere.med.uni-giessen.de. [12]
DOI 10.1038/s41467-019-10839-0
PMID 31278260
发布时间 2021-01-10
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