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首页> Neurobiology of learning and memory> Activation of microglia in acute hippocampal slices affects activity-dependent long-term potentiation and synaptic tagging and capture in area CA1.

Activation of microglia in acute hippocampal slices affects activity-dependent long-term potentiation and synaptic tagging and capture in area CA1.

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作者： Radha,Raghuraman ^[1] ; Aparna,Karthikeyan ^[2] ; Wong Lik,Wei ^[1] ; S Thameem,Dheen ^[3] ; Sreedharan,Sajikumar ^[4]

作者单位： Department of Physiology, National University of Singapore, Singapore 117593, Singapore; Life Sciences Institute Neurobiology Programme, Centre for Life Sciences, National University of Singapore, Singapore 117456, Singapore. ^[1] Department of Anatomy, Yong Loo Lin School of Medicine, National University of Singapore, Singapore. ^[2] Department of Anatomy, Yong Loo Lin School of Medicine, National University of Singapore, Singapore. Electronic address: antstd@nus.edu.sg. ^[3] Department of Physiology, National University of Singapore, Singapore 117593, Singapore; Life Sciences Institute Neurobiology Programme, Centre for Life Sciences, National University of Singapore, Singapore 117456, Singapore. Electronic address: phssks@nus.edu.sg. ^[4]

关键词 Long term potentiation Microglia Neuron-glial interaction Synaptic tagging/capture

主题词动物(Animals);星形细胞(Astrocytes);CA1区, 海马(CA1 Region, Hippocampal);氯膦酸(Clodronic Acid);荧光抗体技术(Fluorescent Antibody Technique);海马(Hippocampus);白细胞介素1β(Interleukin-1beta);长时程增强(Long-Term Potentiation);男(雄)性(Male);小神经胶质细胞(Microglia);神经元(Neurons);少突神经胶质(Oligodendroglia);大鼠(Rats);大鼠, Wistar(Rats, Wistar);突触(Synapses);肿瘤坏死因子α(Tumor Necrosis Factor-alpha)

DOI 10.1016/j.nlm.2019.107039

PMID 31278985

发布时间 2020-04-02

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Neurobiology of learning and memory

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