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首页> Neurobiology of aging> Cross-sectional associations between [<sup>18</sup>F]GTP1 tau PET and cognition in Alzheimer's disease.

Cross-sectional associations between [<sup>18</sup>F]GTP1 tau PET and cognition in Alzheimer's disease.

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作者： Edmond,Teng ^[1] ; Michael,Ward ^[2] ; Paul T,Manser ^[3] ; Sandra,Sanabria-Bohorquez ^[4] ; Rebecca D,Ray ^[5] ; Kristin R,Wildsmith ^[6] ; Suzanne,Baker ^[7] ; Geoffrey A,Kerchner ^[2] ; Robby M,Weimer ^[8]

作者单位： Early Clinical Development, Genentech, Inc., South San Francisco, CA, USA. Electronic address: teng.edmond@gene.com. ^[1] Early Clinical Development, Genentech, Inc., South San Francisco, CA, USA. ^[2] Biostatistics, Genentech, Inc., South San Francisco, CA, USA. ^[3] Clinical Imaging Group, Genentech, Inc., South San Francisco, CA, USA. ^[4] Clinical Imaging Group, Genentech, Inc., South San Francisco, CA, USA; Early Clinical Development Informatics, Genentech, Inc., South San Francisco, CA, USA. ^[5] Biomarker Development, Genentech, Inc., South San Francisco, CA, USA. ^[6] Clinical Imaging Group, Genentech, Inc., South San Francisco, CA, USA; Molecular Biophysics and Integrated Bioimaging, Lawrence Berkeley National Laboratory, Berkeley, CA, USA. ^[7] Department of Biomedical Imaging, Genentech, Inc, South San Francisco, CA, USA. ^[8]

关键词 Alzheimer's disease Clinical trial Cognition PET Tau

主题词老年人(Aged);老年人, 80以上(Aged, 80 and over);阿尔茨海默病(Alzheimer Disease);脑(Brain);认知(Cognition);横断面研究(Cross-Sectional Studies);女(雌)性(Female);氟放射性同位素(Fluorine Radioisotopes);人类(Humans);男(雄)性(Male);中年人(Middle Aged);正电子发射断层显像术(Positron-Emission Tomography);放射性药物(Radiopharmaceuticals);疾病严重程度指数(Severity of Illness Index);tau蛋白质类(tau Proteins)

DOI 10.1016/j.neurobiolaging.2019.05.026

PMID 31280117

发布时间 2020-05-06

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Neurobiology of aging

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