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首页> European journal of medicinal chemistry> Steroidal N-Sulfonylimidates: Synthesis and biological evaluation in breast cancer cells.

Steroidal N-Sulfonylimidates: Synthesis and biological evaluation in breast cancer cells.

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作者： Yulia A,Volkova ^[1] ; Andrey S,Kozlov ^[2] ; Marya K,Kolokolova ^[2] ; Denis Y,Uvarov ^[2] ; Sergey A,Gorbatov ^[2] ; Olga E,Andreeva ^[3] ; Alexander M,Scherbakov ^[4] ; Igor V,Zavarzin ^[2]

作者单位： N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47 Leninsky prosp, 119991, Moscow, Russia. Electronic address: yavolkova@gmail.com. ^[1] N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 47 Leninsky prosp, 119991, Moscow, Russia. ^[2] Department of Experimental Tumor Biology, N.N. Blokhin National Medical Research Center of Oncology of the Ministry of Health of the Russian Federation, 24 Kashirskoye sh, Moscow, 115522, Russia. ^[3] Department of Experimental Tumor Biology, N.N. Blokhin National Medical Research Center of Oncology of the Ministry of Health of the Russian Federation, 24 Kashirskoye sh, Moscow, 115522, Russia. Electronic address: alex.scherbakov@gmail.com. ^[4]

关键词 Antiproliferative potency Azide–alkyne cycloaddition Breast cancer Estrogen receptor Heterosteroids

主题词抗肿瘤药(Antineoplastic Agents);细胞系, 肿瘤(Cell Line, Tumor);细胞增殖(Cell Proliferation);剂量效应关系, 药物(Dose-Response Relationship, Drug);药物筛选试验, 抗肿瘤(Drug Screening Assays, Antitumor);人类(Humans);酰亚胺酯类(Imidoesters);分子结构(Molecular Structure);甾类(Steroids);构效关系(Structure-Activity Relationship)

DOI 10.1016/j.ejmech.2019.06.048

PMID 31284080

发布时间 2019-11-04

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European journal of medicinal chemistry

694-706页

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