作者:
Derek,Klarin [1]
;
Julie,Lynch [2]
;
Krishna,Aragam [3]
;
Mark,Chaffin [4]
;
Themistocles L,Assimes [5]
;
Jie,Huang [6]
;
Kyung Min,Lee [7]
;
Qing,Shao [2]
;
Jennifer E,Huffman [3]
;
Pradeep,Natarajan [3]
;
Shipra,Arya [8]
;
Aeron,Small [9]
;
Yan V,Sun [10]
;
Marijana,Vujkovic [5]
;
Matthew S,Freiberg [7]
;
Lu,Wang [11]
;
Jinbo,Chen [7]
;
Danish,Saleheen [10]
;
Jennifer S,Lee [1]
;
Donald R,Miller [2]
;
Peter,Reaven [12]
;
Patrick R,Alba [8]
;
Olga V,Patterson [13]
;
Scott L,DuVall [14]
;
William E,Boden [15]
;
Joshua A,Beckman [16]
;
J Michael,Gaziano [17]
;
John,Concato [18]
;
Daniel J,Rader [14]
;
Kelly,Cho [19]
;
Kyong-Mi,Chang [20]
;
Peter W F,Wilson [21]
;
Christopher J,O'Donnell [19]
;
Sekar,Kathiresan [19]
;
VA Million Veteran Program [14]
;
Philip S,Tsao [19]
;
Scott M,Damrauer [9]
作者单位:
Boston VA Healthcare System, Boston, MA, USA.
[1]
Center for Genomic Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
[2]
Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.
[3]
Department of Surgery, Massachusetts General Hospital, Boston, MA, USA.
[4]
VA Informatics and Computing Infrastructure, Department of Veterans Affairs, Salt Lake City Health Care System, Salt Lake City, CT, USA.
[5]
University of Massachusetts College of Nursing & Health Sciences, Boston, MA, USA.
[6]
Center for Healthcare Organization and Implementation Research, Edith Nourse Rogers Memorial VA Hospital, Bedford, MA, USA.
[7]
VA Palo Alto Health Care System, Palo Alto, CA, USA.
[8]
Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA.
[9]
Massachusetts Veterans Epidemiology Research and Information Center, VA Boston Healthcare System, Boston, MA, USA.
[10]
Department of Health Law, Policy & Management, Boston University School of Public Health, Boston, MA, USA.
[11]
Cardiovascular Research Center, Massachusetts General Hospital, Boston, MA, USA.
[12]
Department of Surgery, Stanford University School of Medicine, Stanford, CA, USA.
[13]
Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA, USA.
[14]
Department of Medicine, Yale University School of Medicine, New Haven, CT, USA.
[15]
Atlanta VA Health Care System, Decatur, GA, USA.
[16]
Department of Epidemiology, Emory University Rollins School of Public Health, Emory University School of Medicine, Atlanta, GA, USA.
[17]
Department of Biomedical Informatics, Emory University School of Medicine, Atlanta, GA, USA.
[18]
Department of Biostatistics, Epidemiology, and Informatics, Perelman School of Medicine, Philadelphia, PA, USA.
[19]
VA Tennessee Valley Healthcare System, Nashville, TN, USA.
[20]
Vanderbilt University Medical Center, Nashville, TN, USA.
[21]
Center for Healthcare Organization and Implementation Research, Edith Nourse Rogers Memorial Veterans Hospital, Bedford, MA, USA.
[22]
Boston University School of Medicine, Boston, MA, USA.
[23]
Phoenix Veterans Affairs Health Care System, Phoenix, AZ, USA.
[24]
Division of Epidemiology, Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, UT, USA.
[25]
Cardiovascular Division, Vanderbilt University Medical Center, Nashville, TN, USA.
[26]
Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
[27]
Clinical Epidemiology Research Center, VA Connecticut Healthcare System, West Haven, CT, USA.
[28]
Center for Drug Evaluation and Research, US Food and Drug Administration, Silver Spring, MD, USA.
[29]
Department of Medicine, Perlman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
[30]
Emory Clinical Cardiovascular Research Institute, Atlanta, GA, USA.
[31]
Cardiovascular Medicine Division, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
[32]
Corporal Michael J. Crescenz VA Medical Center, Philadelphia, PA, USA. damrauer@upenn.edu.
[33]
Department of Surgery, Perlman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. damrauer@upenn.edu.
[34]
主题词
老年人(Aged);胆固醇, LDL(Cholesterol, LDL);因子Ⅴ(Factor V);疾病遗传易感性(Genetic Predisposition to Disease);全基因组关联研究(Genome-Wide Association Study);人类(Humans);中年人(Middle Aged);外周动脉疾病(Peripheral Arterial Disease);受体, LDL(Receptors, LDL);退伍军人(Veterans)
DOI
10.1038/s41591-019-0492-5
PMID
31285632
发布时间
2022-04-20
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Nature medicine
Nature medicine
1274-1279页
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