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Paternal-age-related de novo mutations and risk for five disorders.

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第一作者: Jacob L,Taylor
第一单位: Department of Psychiatry, Brigham and Woman's Hospital, Boston, MA, 02115, USA.;Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA.;Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, 02412, USA.
作者单位: Department of Psychiatry, Brigham and Woman's Hospital, Boston, MA, 02115, USA.;Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA.;Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, 02412, USA. [1] National Centre for Register-based Research, Department of Economics and Business, Aarhus University, Aarhus, 8210, Denmark.;The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Aarhus, 8210, Denmark.;Aarhus University Hospital, Risskov, Department P, Aarhus, 8200, Denmark. [2] Division of Newborn Medicine, Boston Children's Hospital and Harvard Medical School, Boston, MA, 02115, USA. [3] Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA.;Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, 02412, USA.;Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, 02114, USA. [4] Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA.;Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, 02114, USA.;Cologne Center for Genomics, University of Cologne, Cologne, 50923, Germany.;Psychiatric and Neurodevelopmental Genetics Unit, Department of Psychiatry, Massachusetts General Hospital, Boston, MA, 02114, USA. [5] Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA.;Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, 02114, USA. [6] National Centre for Register-based Research, Department of Economics and Business, Aarhus University, Aarhus, 8210, Denmark.;The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Aarhus, 8210, Denmark. [7] Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA.;Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, 02412, USA.;Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, 02114, USA.;Program in Genetics and Genomics, Biological and Biomedical Sciences, Harvard Medical School, Boston, MA, 02115, USA. [8] Department of Genetics, Harvard Medical School, Boston, MA, 02115, USA. [9] Department of Genetics, Harvard Medical School, Boston, MA, 02115, USA.;Cardiovascular Division, Brigham and Women's Hospital, Boston, MA, 02115, USA.;Howard Hughes Medical Institute, Harvard Medical School, Boston, MA, 02115, USA. [10] National Centre for Register-based Research, Department of Economics and Business, Aarhus University, Aarhus, 8210, Denmark.;The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Aarhus, 8210, Denmark.;Centre for Integrated Register-based Research, CIRRAU, Aarhus University, Aarhus, 8210, Denmark. [11] National Centre for Register-based Research, Department of Economics and Business, Aarhus University, Aarhus, 8210, Denmark.;Queensland Brain Institute, The University of Queensland, Brisbane, 4072, Queensland, Australia.;Queensland Centre for Mental Health Research, The Park Centre for Mental Health, Richlands, 4076, Queensland, Australia. [12] National Centre for Register-based Research, Department of Economics and Business, Aarhus University, Aarhus, 8210, Denmark.;The Lundbeck Foundation Initiative for Integrative Psychiatric Research, iPSYCH, Aarhus, 8210, Denmark.;Centre for Integrated Register-based Research, CIRRAU, Aarhus University, Aarhus, 8210, Denmark.;Department of Biomedicine and iSEQ, Centre for Integrative Sequencing, Aarhus University, Aarhus, 08210, Denmark. [13] Stanley Center for Psychiatric Research, Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA. erobinso@hsph.harvard.edu.;Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, 02412, USA. erobinso@hsph.harvard.edu.;Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, 02114, USA. erobinso@hsph.harvard.edu.;Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA, 02115, USA. erobinso@hsph.harvard.edu. [14]
DOI 10.1038/s41467-019-11039-6
PMID 31292440
发布时间 2022-12-07
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