Combined ischemic and rapamycin preconditioning alleviated liver ischemia and reperfusion injury by restoring autophagy in aged mice.
第一作者:
Tao,Jiang
第一单位:
Hepatobiliary/Liver Transplantation Center, the First Affiliated Hospital of Nanjing Medical University, Nanjing, China; Department of Surgical Oncology, the Bayi Hospital, Nanjing University of Chinese Medicine, Nanjing, China.
作者:
医学主题词
衰老(Aging);动物(Animals);自噬(Autophagy);半胱氨酸天冬氨酸蛋白酶3(Caspase 3);细胞, 培养的(Cells, Cultured);综合疗法(Combined Modality Therapy);疾病模型, 动物(Disease Models, Animal);人类(Humans);免疫抑制剂(Immunosuppressive Agents);缺血预处理(Ischemic Preconditioning);肝(Liver);男(雄)性(Male);小鼠(Mice);小鼠, 近交C57BL(Mice, Inbred C57BL);微管相关蛋白质类(Microtubule-Associated Proteins);再灌注损伤(Reperfusion Injury);西罗莫司(Sirolimus)
DOI
10.1016/j.intimp.2019.105711
PMID
31302450
发布时间
2020-12-30
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