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首页> Journal of clinical microbiology> A Novel Broad Allele-Specific TaqMan Real-Time PCR Method To Detect Triazole-Resistant Strains of Aspergillus fumigatus, Even with a Very Low Percentage of Triazole-Resistant Cells Mixed with Triazole-Susceptible Cells.

A Novel Broad Allele-Specific TaqMan Real-Time PCR Method To Detect Triazole-Resistant Strains of Aspergillus fumigatus, Even with a Very Low Percentage of Triazole-Resistant Cells Mixed with Triazole-Susceptible Cells.

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作者： Qian,Wang ^[1] ; Dimitrios P,Kontoyiannis ^[2] ; Ruoyu,Li ^[3] ; Wei,Chen ^[4] ; Dingfang,Bu ^[1] ; Wei,Liu ^[2]

作者单位： Department of Dermatology, Peking University First Hospital, Beijing, China. ^[1] Research Center for Medical Mycology, Peking University, Beijing, China. ^[2] Beijing Key Laboratory of Molecular Diagnosis on Dermatoses, Beijing, China. ^[3] Department of Infectious Disease, Infection Control and Employee Health, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA. ^[4] Department of Dermatology, Peking University First Hospital, Beijing, China liuwei@bjmu.edu.cn. ^[5]

关键词 A. fumigatus allele-specific real-time PCR cyp51A mutations mixed infection triazole resistance

主题词等位基因(Alleles);抗真菌药(Antifungal Agents);曲霉菌病(Aspergillosis);烟曲霉菌(Aspergillus fumigatus);细胞色素P450酶系统(Cytochrome P-450 Enzyme System);抗药性, 真菌(Drug Resistance, Fungal);真菌蛋白质类(Fungal Proteins);人类(Humans);分子诊断技术(Molecular Diagnostic Techniques);敏感性与特异性(Sensitivity and Specificity);时间因素(Time Factors);三唑类(Triazoles)

DOI 10.1128/JCM.00604-19

PMID 31315952

发布时间 2020-07-07

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Journal of clinical microbiology

Journal of clinical microbiology

2019年57卷9期

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