Intraarticular injection of processed lipoaspirate cells has anti-inflammatory and analgesic effects but does not improve degenerative changes in murine monoiodoacetate-induced osteoarthritis.

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第一作者： Takumi,Sakamoto

第一单位： Department of Orthopaedics and Rehabilitation Medicine, Faculty of Medical Sciences, University of Fukui, Matsuoka Shimoaizuki 23-3, Eiheiji, Fukui, 910-1193, Japan.

作者： Takumi,Sakamoto ^[1] ; Tsuyoshi,Miyazaki ^[2] ; Shuji,Watanabe ^[1] ; Ai,Takahashi ^[1] ; Kazuya,Honjoh ^[1] ; Hideaki,Nakajima ^[1] ; Hisashi,Oki ^[1] ; Yasuo,Kokubo ^[1] ; Akihiko,Matsumine ^[1]

作者单位： Department of Orthopaedics and Rehabilitation Medicine, Faculty of Medical Sciences, University of Fukui, Matsuoka Shimoaizuki 23-3, Eiheiji, Fukui, 910-1193, Japan. ^[1] Department of Orthopaedics and Rehabilitation Medicine, Faculty of Medical Sciences, University of Fukui, Matsuoka Shimoaizuki 23-3, Eiheiji, Fukui, 910-1193, Japan. mtuyo@u-fukui.ac.jp. ^[2]

关键词 Adipose derived-mesenchymal stem cells (AD-MSCs)Calcitonin gene-related peptide (CGRP)Dorsal root ganglion (DRG)Intra-articular injection Mesenchymal stem cells (MSCs)Monoiodoacetate (MIA)Osteoarthritis (OA)Processed lipoaspirate (PLA) cells Sprague-Dawley rats Substance P (SP)