Apatinib inhibits glycolysis by suppressing the VEGFR2/AKT1/SOX5/GLUT4 signaling pathway in ovarian cancer cells.
第一作者:
Lihua,Chen
第一单位:
Department of Gynecological Oncology and Department of Medical Oncology, Fudan University Shanghai Cancer Center, 270 Dong'an Road, Shanghai, 200032, China.;Department of Oncology, Shanghai Medical College, Fudan University, 270 Dong'an Road, Shanghai, 200032, China.
作者:
医学主题词
动物(Animals);抗肿瘤药(Antineoplastic Agents);细胞系, 肿瘤(Cell Line, Tumor);细胞运动(Cell Movement);细胞增殖(Cell Proliferation);细胞存活(Cell Survival);女(雌)性(Female);葡萄糖转运体4型(Glucose Transporter Type 4);糖酵解(Glycolysis);人类(Humans);小鼠, 近交BALB C(Mice, Inbred BALB C);小鼠, 裸(Mice, Nude);卵巢肿瘤(Ovarian Neoplasms);原癌基因蛋白质c-akt(Proto-Oncogene Proteins c-akt);吡啶类(Pyridines);SOXD转录因子类(SOXD Transcription Factors);信号传导(Signal Transduction);血管内皮生长因子受体2(Vascular Endothelial Growth Factor Receptor-2)
DOI
10.1007/s13402-019-00455-x
PMID
31325096
发布时间
2026-03-31
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