The Combined Effect of FGFR Inhibition and PD-1 Blockade Promotes Tumor-Intrinsic Induction of Antitumor Immunity.-论文-万方医学网

第一作者： Sangeetha,Palakurthi

第一单位： Belfer Center for Applied Cancer Science, Dana-Farber Cancer Institute, Boston, Massachusetts.

作者： Sangeetha,Palakurthi ^[1] ; Mari,Kuraguchi ^[1] ; Sima J,Zacharek ^[1] ; Enrique,Zudaire ^[2] ; Wei,Huang ^[1] ; Dennis M,Bonal ^[3] ; Jeffrey,Liu ^[1] ; Abha,Dhaneshwar ^[1] ; Kristin,DePeaux ^[1] ; Martha R,Gowaski ^[1] ; Dyane,Bailey ^[1] ; Samuel N,Regan ^[1] ; Elena,Ivanova ^[1] ; Catherine,Ferrante ^[2] ; Jessie M,English ^[1] ; Aditya,Khosla ^[4] ; Andrew H,Beck ^[4] ; Julie A,Rytlewski ^[5] ; Catherine,Sanders ^[5] ; Sylvie,Laquerre ^[2] ; Mark A,Bittinger ^[1] ; Paul T,Kirschmeier ^[1] ; Kathryn,Packman ^[2] ; Pasi A,Janne ^[1] ; Christopher,Moy ^[6] ; Kwok-Kin,Wong ^[2] ; Raluca I,Verona ^[1] ; Matthew V,Lorenzi ^[7]

作者单位： Belfer Center for Applied Cancer Science, Dana-Farber Cancer Institute, Boston, Massachusetts. ^[1] Janssen, Pharmaceutical Companies of Johnson & Johnson, Spring House, Pennsylvania. ^[2] Lurie Family Imaging Center, Dana-Farber Cancer Institute, Boston, Massachusetts. ^[3] PathAI, Boston, Massachusetts. ^[4] Adaptive Biotechnologies, Seattle, Washington. ^[5] Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts. ^[6] Laura & Isaac Perlmutter Cancer Center, NYU Langone Medical Center, New York University, New York, New York. ^[7] Janssen, Pharmaceutical Companies of Johnson & Johnson, Spring House, Pennsylvania. rverona@its.jnj.com mlorenzi@its.jnj.com. ^[8]

主题词动物(Animals);细胞系, 肿瘤(Cell Line, Tumor);疾病模型, 动物(Disease Models, Animal);药物协同作用(Drug Synergism);人类(Humans);免疫(Immunity);免疫表型分型(Immunophenotyping);淋巴细胞, 肿瘤浸润(Lymphocytes, Tumor-Infiltrating);小鼠(Mice);小鼠, 转基因(Mice, Transgenic);突变(Mutation);肿瘤(Neoplasms);预后(Prognosis);吡唑类(Pyrazoles);喹恶啉类(Quinoxalines);受体, 抗原, T细胞(Receptors, Antigen, T-Cell);受体, 成纤维细胞生长因子(Receptors, Fibroblast Growth Factor);信号传导(Signal Transduction);T淋巴细胞亚群(T-Lymphocyte Subsets);治疗结果(Treatment Outcome);肿瘤微环境(Tumor Microenvironment)

DOI 10.1158/2326-6066.CIR-18-0595

PMID 31331945

发布时间 2020-09-07

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The Combined Effect of FGFR Inhibition and PD-1 Blockade Promotes Tumor-Intrinsic Induction of Antitumor Immunity.

Cancer immunology research

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Cancer immunology research

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The Combined Effect of FGFR Inhibition and PD-1 Blockade Promotes Tumor-Intrinsic Induction of Antitumor Immunity.

Cancer immunology research

相似文献

Cancer immunology research

相关期刊

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