首页> Molecular immunology> Identification of a distinct subset of disease-associated gain-of-function missense mutations in the STAT1 coiled-coil domain as system mutants.

Identification of a distinct subset of disease-associated gain-of-function missense mutations in the STAT1 coiled-coil domain as system mutants.

导出 LinkOut

翻译打印收藏纠错

第一作者： Jana,Petersen

第一单位： Department of Psychosomatic Medicine and Psychotherapy, University Medical Center Göttingen, Göttingen, Germany.

作者： Jana,Petersen ^[1] ; Julia,Staab ^[1] ; Oliver,Bader ^[2] ; Timo,Buhl ^[3] ; Aleksandar,Ivetic ^[4] ; Thomas,Meyer ^[5]

作者单位： Department of Psychosomatic Medicine and Psychotherapy, University Medical Center Göttingen, Göttingen, Germany. ^[1] Institute of Medical Microbiology, University Medical Center Göttingen, Göttingen, Germany. ^[2] Department of Dermatology, Venereology and Allergology, University Medical Center Göttingen, Göttingen, Germany. ^[3] School of Cardiovascular Medicine and Sciences, James Black Centre, BHF Centre of Research Excellence, King's College London, London, UK. ^[4] Department of Psychosomatic Medicine and Psychotherapy, University Medical Center Göttingen, Göttingen, Germany. Electronic address: thomas.meyer@med.uni-goettingen.de. ^[5]

关键词 Chronic mucocutaneous candidiasis Dimerization Gain-of-function mutation Interferon signalling STAT1