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首页> Clinical infectious diseases : an official publication of the Infectious Diseases Society of America> First-in-Human Randomized Study to Assess the Safety and Immunogenicity of an Investigational Respiratory Syncytial Virus (RSV) Vaccine Based on Chimpanzee-Adenovirus-155 Viral Vector-Expressing RSV Fusion, Nucleocapsid, and Antitermination Viral Proteins in Healthy Adults.

First-in-Human Randomized Study to Assess the Safety and Immunogenicity of an Investigational Respiratory Syncytial Virus (RSV) Vaccine Based on Chimpanzee-Adenovirus-155 Viral Vector-Expressing RSV Fusion, Nucleocapsid, and Antitermination Viral Proteins in Healthy Adults.

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作者： Paola,Cicconi ^[1] ; Claire,Jones ^[1] ; Esha,Sarkar ^[1] ; Laura,Silva-Reyes ^[1] ; Paul,Klenerman ^[2] ; Catherine,de Lara ^[2] ; Claire,Hutchings ^[2] ; Philippe,Moris ^[3] ; Michel,Janssens ^[3] ; Laurence A,Fissette ^[4] ; Marta,Picciolato ^[3] ; Amanda,Leach ^[5] ; Antonio,Gonzalez-Lopez ^[5] ; Ilse,Dieussaert ^[5] ; Matthew D,Snape ^[1]

作者单位： Oxford Vaccine Group, Department of Paediatrics, University of Oxford, United Kingdom. ^[1] Nuffield Department of Medicine, University of Oxford, United Kingdom. ^[2] GSK, Rixensart, Belgium. ^[3] GSK, Wavre, Belgium. ^[4] GSK, Rockville, Maryland. ^[5] National Institute for Health Research Oxford Biomedical Centre, United Kingdom. ^[6]

关键词 RSV first-in-human study viral vector vaccine

主题词腺病毒科(Adenoviridae);青少年(Adolescent);成年人(Adult);动物(Animals);抗体, 中和(Antibodies, Neutralizing);抗体, 病毒(Antibodies, Viral);人类(Humans);白细胞, 单核(Leukocytes, Mononuclear);中年人(Middle Aged);核壳(Nucleocapsid);黑猩猩属(Pan troglodytes);呼吸道合胞体病毒感染(Respiratory Syncytial Virus Infections);呼吸道合胞病毒疫苗(Respiratory Syncytial Virus Vaccines);病毒蛋白质类(Viral Proteins);病毒粒子(Virion);青年人(Young Adult)

DOI 10.1093/cid/ciz653

PMID 31340042

发布时间 2022-02-16

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Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

Clinical infectious diseases

2020年70卷10期

2073-2081页

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