Abatacept in Early Diffuse Cutaneous Systemic Sclerosis: Results of a Phase II Investigator-Initiated, Multicenter, Double-Blind, Randomized, Placebo-Controlled Trial.

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第一作者： Dinesh,Khanna

第一单位： University of Michigan, Ann Arbor.

作者： Dinesh,Khanna ^[1] ; Cathie,Spino ^[1] ; Sindhu,Johnson ^[2] ; Lorinda,Chung ^[3] ; Michael L,Whitfield ^[4] ; Christopher P,Denton ^[5] ; Veronica,Berrocal ^[1] ; Jennifer,Franks ^[4] ; Bhavan,Mehta ^[4] ; Jerry,Molitor ^[6] ; Virginia D,Steen ^[7] ; Robert,Lafyatis ^[8] ; Robert W,Simms ^[9] ; Anna,Gill ^[5] ; Suzanne,Kafaja ^[10] ; Tracy M,Frech ^[11] ; Vivien,Hsu ^[12] ; Robyn T,Domsic ^[13] ; Janet E,Pope ^[14] ; Jessica K,Gordon ^[15] ; Maureen D,Mayes ^[16] ; Elena,Schiopu ^[1] ; Amber,Young ^[1] ; Nora,Sandorfi ^[17] ; Jane,Park ^[18] ; Faye N,Hant ^[19] ; Elana J,Bernstein ^[20] ; Soumya,Chatterjee ^[21] ; Flavia V,Castelino ^[22] ; Ali,Ajam ^[23] ; Yue,Wang ^[4] ; Tammara,Wood ^[4] ; Yannick,Allanore ^[24] ; Marco,Matucci-Cerinic ^[25] ; Oliver,Distler ^[26] ; Ora,Singer ^[1] ; Erica,Bush ^[1] ; David A,Fox ^[1] ; Daniel E,Furst ^[27]

作者单位： University of Michigan, Ann Arbor. ^[1] Mount Sinai Hospital and University Health Network, Toronto, Ontario, Canada. ^[2] Stanford University School of Medicine, Palo Alto, California. ^[3] Geisel School of Medicine at Dartmouth, Hanover, New Hampshire. ^[4] Royal Free Campus, London, UK. ^[5] University of Minnesota, Minneapolis. ^[6] MedStar Georgetown University Hospital, Washington, DC. ^[7] Pittsburgh University Medical Center, Pittsburgh, Pennsylvania. ^[8] Boston University School of Medicine, Boston, Massachusetts. ^[9] David Geffen School of Medicine at University of California, Los Angeles. ^[10] University of Utah, Salt Lake City. ^[11] Robert Wood Johnson University, New Brunswick, New Jersey. ^[12] University of Pittsburgh, Pittsburgh, Pennsylvania. ^[13] University of Western Ontario, London, Ontario, Canada. ^[14] Hospital for Special Surgery, New York, New York. ^[15] University of Texas McGovern Medical School, Houston. ^[16] Perelman School of Medicine at the University of Pennsylvania, Pittsburgh. ^[17] Seattle Rheumatology Associates, Seattle, Washington. ^[18] Medical University of South Carolina, Charleston. ^[19] Columbia University, New York, New York. ^[20] Cleveland Clinic, Cleveland, Ohio. ^[21] Harvard Medical School, Boston, Massachusetts. ^[22] Ohio State University Wexner Medical Center, Columbus. ^[23] Hôpital Cochin, Paris, France. ^[24] University of Florence, Florence, Italy. ^[25] University Hospital Zurich, Zurich, Switzerland. ^[26] University of California, Los Angeles. ^[27]

主题词成年人(Adult);双盲法(Double-Blind Method);女(雌)性(Female);基因表达(Gene Expression);基因表达谱(Gene Expression Profiling);人类(Humans);男(雄)性(Male);中年人(Middle Aged);硬皮病, 弥散性(Scleroderma, Diffuse);序列分析, RNA(Sequence Analysis, RNA);疾病严重程度指数(Severity of Illness Index);皮肤(Skin);治疗结果(Treatment Outcome);肺活量(Vital Capacity)

DOI 10.1002/art.41055

PMID 31342624

发布时间 2024-09-22

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Arthritis & rheumatology (Hoboken, N.J.)

2020年72卷1期

125-136页

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Abatacept in Early Diffuse Cutaneous Systemic Sclerosis: Results of a Phase II Investigator-Initiated, Multicenter, Double-Blind, Randomized, Placebo-Controlled Trial.

Arthritis & rheumatology (Hoboken, N.J.)

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Abatacept in Early Diffuse Cutaneous Systemic Sclerosis: Results of a Phase II Investigator-Initiated, Multicenter, Double-Blind, Randomized, Placebo-Controlled Trial.

Arthritis & rheumatology (Hoboken, N.J.)

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Arthritis & rheumatology (Hoboken, N.J.)

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