Hepatitis B virus-induced modulation of liver macrophage function promotes hepatocyte infection.

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第一作者： Suzanne,Faure-Dupuy

第一单位： INSERM, U1052, Cancer Research Center of Lyon (CRCL), Université de Lyon (UCBL1), CNRS UMR_5286, France; Division of Chronic Inflammation and Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany.

作者： Suzanne,Faure-Dupuy ^[1] ; Marion,Delphin ^[2] ; Ludovic,Aillot ^[2] ; Laura,Dimier ^[2] ; Fanny,Lebossé ^[3] ; Judith,Fresquet ^[2] ; Romain,Parent ^[2] ; Matthias Sebastian,Matter ^[4] ; Michel,Rivoire ^[5] ; Nathalie,Bendriss-Vermare ^[2] ; Anna,Salvetti ^[2] ; Danijela,Heide ^[6] ; Lalo,Flores ^[7] ; Klaus,Klumpp ^[7] ; Angela,Lam ^[7] ; Fabien,Zoulim ^[8] ; Mathias,Heikenwälder ^[6] ; David,Durantel ^[9] ; Julie,Lucifora ^[10]

作者单位： INSERM, U1052, Cancer Research Center of Lyon (CRCL), Université de Lyon (UCBL1), CNRS UMR_5286, France; Division of Chronic Inflammation and Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany. ^[1] INSERM, U1052, Cancer Research Center of Lyon (CRCL), Université de Lyon (UCBL1), CNRS UMR_5286, France. ^[2] INSERM, U1052, Cancer Research Center of Lyon (CRCL), Université de Lyon (UCBL1), CNRS UMR_5286, France; Department of Hepatology, Croix-Rousse Hospital, Hospices Civils de Lyon, Lyon, France. ^[3] University Hospital of Basel, Institute of Pathology, Basel, Switzerland. ^[4] INSERM U1032, Centre Léon Bérard (CLB), Lyon, France. ^[5] Division of Chronic Inflammation and Cancer, German Cancer Research Center (DKFZ), Heidelberg, Germany. ^[6] Novira Therapeutics, Part of the Janssen Pharmaceutical Companies, United States. ^[7] INSERM, U1052, Cancer Research Center of Lyon (CRCL), Université de Lyon (UCBL1), CNRS UMR_5286, France; Department of Hepatology, Croix-Rousse Hospital, Hospices Civils de Lyon, Lyon, France; DEVweCAN Laboratory of Excellence, Lyon, France. ^[8] INSERM, U1052, Cancer Research Center of Lyon (CRCL), Université de Lyon (UCBL1), CNRS UMR_5286, France; DEVweCAN Laboratory of Excellence, Lyon, France. Electronic address: david.durantel@inserm.fr. ^[9] INSERM, U1052, Cancer Research Center of Lyon (CRCL), Université de Lyon (UCBL1), CNRS UMR_5286, France. Electronic address: julie.lucifora@inserm.fr. ^[10]

关键词 Anti-inflammatory Anti-viral effect Hepatitis B virus (HBV)IL-10 IL-1β Liver macrophage Phenotypic immune-modulation