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Lactobacillus rescues postnatal neurobehavioral and microglial dysfunction in a model of maternal microbiome dysbiosis.

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第一作者： Yeonwoo,Lebovitz

第一单位： Graduate Program in Translational Biology, Medicine, and Health, Virginia Tech, Blacksburg, VA 24061, USA.

作者： Yeonwoo,Lebovitz ^[1] ; Elizabeth A,Kowalski ^[2] ; Xia,Wang ^[2] ; Colin,Kelly ^[3] ; Madison,Lee ^[3] ; Valerie,McDonald ^[4] ; Rachael,Ward ^[3] ; Miranda,Creasey ^[5] ; William,Mills ^[1] ; Erwin Kristobal,Gudenschwager Basso ^[2] ; Amanda,Hazy ^[2] ; Terry,Hrubec ^[6] ; Michelle H,Theus ^[7]

作者单位： Graduate Program in Translational Biology, Medicine, and Health, Virginia Tech, Blacksburg, VA 24061, USA. ^[1] Department of Biomedical Sciences and Pathobiology, VA-MD College of Veterinary Medicine, Blacksburg, VA 24061, USA. ^[2] School of Neuroscience, Virginia Tech, Blacksburg, VA 24061, USA. ^[3] Department of Biomedical Sciences, Edward Via College of Osteopathic Medicine, Blacksburg, VA 24060, USA. ^[4] Virginia Tech Carilion School of Medicine, Roanoke, VA 24016, USA. ^[5] Department of Biomedical Sciences and Pathobiology, VA-MD College of Veterinary Medicine, Blacksburg, VA 24061, USA; Department of Biomedical Sciences, Edward Via College of Osteopathic Medicine, Blacksburg, VA 24060, USA. ^[6] Graduate Program in Translational Biology, Medicine, and Health, Virginia Tech, Blacksburg, VA 24061, USA; Department of Biomedical Sciences and Pathobiology, VA-MD College of Veterinary Medicine, Blacksburg, VA 24061, USA; School of Neuroscience, Virginia Tech, Blacksburg, VA 24061, USA; Center for Regenerative Medicine, VA-MD College of Veterinary Medicine, Blacksburg, VA, 24061, USA. Electronic address: mtheus@vt.edu. ^[7]

关键词 Autism spectrum disorders Cx3cr1 Gut bacteria Microbiota Neurodevelopment Senescence Social behavior Trp53