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Tyrosine Threonine Kinase Inhibition Eliminates Lung Cancers by Augmenting Apoptosis and Polyploidy.

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第一作者： Lin,Zheng

第一单位： Department of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.

作者： Lin,Zheng ^[1] ; Zibo,Chen ^[2] ; Masanori,Kawakami ^[2] ; Yulong,Chen ^[1] ; Jason,Roszik ^[3] ; Lisa Maria,Mustachio ^[1] ; Jonathan M,Kurie ^[1] ; Pamela,Villalobos ^[4] ; Wei,Lu ^[4] ; Carmen,Behrens ^[4] ; Barbara,Mino ^[4] ; Luisa M,Solis ^[4] ; Jennifer,Silvester ^[5] ; Kelsie L,Thu ^[5] ; David W,Cescon ^[5] ; Jaime,Rodriguez-Canales ^[4] ; Ignacio I,Wistuba ^[4] ; Tak W,Mak ^[5] ; Xi,Liu ^[2] ; Ethan,Dmitrovsky ^[6]

作者单位： Department of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas. ^[1] Department of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.;Frederick National Laboratory for Cancer Research, Frederick, Maryland. ^[2] Department of Melanoma Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.;Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas. ^[3] Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas. ^[4] The Campbell Family Institute for Breast Cancer Research at Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada. ^[5] Department of Thoracic/Head and Neck Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas. ethan.dmitrovsky@nih.gov.;Frederick National Laboratory for Cancer Research, Frederick, Maryland.;Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas. ^[6]