TLX3 repressed SNAI1-induced epithelial-mesenchymal transition by directly constraining STAT3 phosphorylation and functionally sensitized 5-FU chemotherapy in hepatocellular carcinoma.
第一作者:
Cong,Wang
第一单位:
Department of Hepatobiliary Surgery, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi 710061, China.
作者:
主题词
动物(Animals);细胞凋亡(Apoptosis);癌, 肝细胞(Carcinoma, Hepatocellular);细胞系, 肿瘤(Cell Line, Tumor);染色质免疫沉淀法(Chromatin Immunoprecipitation);上皮-间质转化(Epithelial-Mesenchymal Transition);氟尿嘧啶(Fluorouracil);同源盒结构域蛋白质类(Homeodomain Proteins);人类(Humans);免疫印迹法(Immunoblotting);免疫沉淀法(Immunoprecipitation);肝肿瘤(Liver Neoplasms);男(雄)性(Male);小鼠(Mice);小鼠, 裸(Mice, Nude);磷酰化(Phosphorylation);蛋白质组学(Proteomics);RNA干扰(RNA Interference);STAT3转录因子(STAT3 Transcription Factor);伤口愈合(Wound Healing)
DOI
10.7150/ijbs.33844
PMID
31360112
发布时间
2020-04-08
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