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A New Benzopyranyl Cadenane Sesquiterpene and Other Antiplasmodial and Cytotoxic Metabolites from Cleistochlamys kirkii.

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第一作者： Stephen S,Nyandoro

第一单位： Chemistry Department, College of Natural and Applied Sciences, University of Dar es Salaam, Dar es Salaam P.O. Box 35061, Tanzania. nyandoro@udsm.ac.tz.;Department of Chemistry and Molecular Biology, University of Gothenburg, SE-412 96 Gothenburg, Sweden. nyandoro@udsm.ac.tz.

作者： Stephen S,Nyandoro ^[1] ; Gasper,Maeda ^[2] ; Joan J E,Munissi ^[3] ; Amra,Gruhonjic ^[4] ; Paul A,Fitzpatrick ^[5] ; Sofia,Lindblad ^[6] ; Sandra,Duffy ^[7] ; Jerry,Pelletier ^[8] ; Fangfang,Pan ^[9] ; Rakesh,Puttreddy ^[10] ; Vicky M,Avery ^[7] ; Máté,Erdélyi ^[11]

作者单位： Chemistry Department, College of Natural and Applied Sciences, University of Dar es Salaam, Dar es Salaam P.O. Box 35061, Tanzania. nyandoro@udsm.ac.tz.;Department of Chemistry and Molecular Biology, University of Gothenburg, SE-412 96 Gothenburg, Sweden. nyandoro@udsm.ac.tz. ^[1] Chemistry Department, College of Natural and Applied Sciences, University of Dar es Salaam, Dar es Salaam P.O. Box 35061, Tanzania.;Department of Chemistry and Molecular Biology, University of Gothenburg, SE-412 96 Gothenburg, Sweden. ^[2] Chemistry Department, College of Natural and Applied Sciences, University of Dar es Salaam, Dar es Salaam P.O. Box 35061, Tanzania. ^[3] Department of Chemistry and Molecular Biology, University of Gothenburg, SE-412 96 Gothenburg, Sweden. ^[4] Sahlgrenska Cancer Centre, University of Gothenburg, SE-405 30 Gothenburg, Sweden. ^[5] Department of Chemistry-BMC, Uppsala University, SE-751 23 Uppsala, Sweden. ^[6] Discovery Biology, Griffith Institute for Drug Discovery, Griffith University, Nathan Q1d 4111, Australia. ^[7] Department of Biochemistry, McGill University, Montréal, QC H3G 1Y6, Canada. ^[8] Key Laboratory of Pesticide & Chemical Biology of Ministry of Education, Hubei International Scientific and Technological Cooperation Base of Pesticide and Green Synthesis, College of Chemistry, Central China Normal University, Luoyu Road 152, Wuhan 430079, China.;Department of Chemistry, University of Jyvaskyla, P.O. Box 35, FI-40014 Jyvaskyla, Finland. ^[9] Department of Chemistry, University of Jyvaskyla, P.O. Box 35, FI-40014 Jyvaskyla, Finland. ^[10] Department of Chemistry and Molecular Biology, University of Gothenburg, SE-412 96 Gothenburg, Sweden. mate.erdelyi@kemi.uu.se.;Department of Chemistry-BMC, Uppsala University, SE-751 23 Uppsala, Sweden. mate.erdelyi@kemi.uu.se. ^[11]

关键词 Annonaceae Cleistochlamys kirkii antiplasmodial activity benzopyranyl sesquiterpene cleistonol cytotoxicity malaria