Intracellular Trapping of the Selective Phosphoglycerate Dehydrogenase (PHGDH) Inhibitor <b>BI-4924</b> Disrupts Serine Biosynthesis.

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第一作者： Harald,Weinstabl

第一单位： Boehringer Ingelheim RCV GmbH & Co. KG , Dr.-Boehringer-Gasse 5-11 , 1121 Vienna , Austria.

作者： Harald,Weinstabl ^[1] ; Matthias,Treu ^[1] ; Joerg,Rinnenthal ^[1] ; Stephan K,Zahn ^[1] ; Peter,Ettmayer ^[1] ; Gerd,Bader ^[1] ; Georg,Dahmann ^[2] ; Dirk,Kessler ^[1] ; Klaus,Rumpel ^[1] ; Nikolai,Mischerikow ^[1] ; Fabio,Savarese ^[1] ; Thomas,Gerstberger ^[1] ; Moriz,Mayer ^[1] ; Andreas,Zoephel ^[1] ; Renate,Schnitzer ^[1] ; Wolfgang,Sommergruber ^[1] ; Paola,Martinelli ^[1] ; Heribert,Arnhof ^[1] ; Biljana,Peric-Simov ^[1] ; Karin S,Hofbauer ^[1] ; Géraldine,Garavel ^[1] ; Yvonne,Scherbantin ^[1] ; Sophie,Mitzner ^[1] ; Thomas N,Fett ^[1] ; Guido,Scholz ^[1] ; Jens,Bruchhaus ^[1] ; Michelle,Burkard ^[1] ; Roland,Kousek ^[1] ; Tuncay,Ciftci ^[2] ; Bernadette,Sharps ^[1] ; Andreas,Schrenk ^[1] ; Christoph,Harrer ^[1] ; Daniela,Haering ^[1] ; Bernhard,Wolkerstorfer ^[1] ; Xuechun,Zhang ^[3] ; Xiaobing,Lv ^[3] ; Alicia,Du ^[3] ; Dongyang,Li ^[3] ; Yali,Li ^[3] ; Jens,Quant ^[1] ; Mark,Pearson ^[1] ; Darryl B,McConnell ^[1]

作者单位： Boehringer Ingelheim RCV GmbH & Co. KG , Dr.-Boehringer-Gasse 5-11 , 1121 Vienna , Austria. ^[1] Boehringer Ingelheim Pharma GmbH & Co. KG , Birkendorfer Str. 65 , 88400 Biberach an der Riß , Germany. ^[2] Shanghai ChemPartner Co., LTD. , No. 5 Building, 998 Halei Road, Zhangjiang Hi-Tech Park, Pudong New Area , Shanghai 201203 , China. ^[3]