Glutamine Synthetase Promotes Radiation Resistance via Facilitating Nucleotide Metabolism and Subsequent DNA Damage Repair.

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第一作者： Shujun,Fu

第一单位： Center for Molecular Medicine, Xiangya Hospital, Central South University, Changsha 410008, China; Key Laboratory of Molecular Radiation Oncology Hunan Province, Changsha 410008, China.

作者： Shujun,Fu ^[1] ; Zhi,Li ^[2] ; Lanbo,Xiao ^[3] ; Wenfeng,Hu ^[1] ; Lu,Zhang ^[1] ; Bowen,Xie ^[1] ; Qin,Zhou ^[4] ; Junju,He ^[5] ; Yanfang,Qiu ^[5] ; Ming,Wen ^[1] ; Yanni,Peng ^[5] ; Jie,Gao ^[5] ; Rong,Tan ^[2] ; Yuezhen,Deng ^[2] ; Liang,Weng ^[2] ; Lun-Quan,Sun ^[6]

作者单位： Center for Molecular Medicine, Xiangya Hospital, Central South University, Changsha 410008, China; Key Laboratory of Molecular Radiation Oncology Hunan Province, Changsha 410008, China. ^[1] Center for Molecular Medicine, Xiangya Hospital, Central South University, Changsha 410008, China; Key Laboratory of Molecular Radiation Oncology Hunan Province, Changsha 410008, China; Hunan International Science and Technology Collaboration Base of Precision Medicine for Cancer, Changsha 410008, China. ^[2] Cancer Research Institute, Xiangya School of Medicine, Central South University, Changsha 410008, China. ^[3] Department of Oncology, Xiangya Hospital, Central South University, Changsha 410008, China. ^[4] Center for Molecular Medicine, Xiangya Hospital, Central South University, Changsha 410008, China. ^[5] Center for Molecular Medicine, Xiangya Hospital, Central South University, Changsha 410008, China; Key Laboratory of Molecular Radiation Oncology Hunan Province, Changsha 410008, China; Hunan International Science and Technology Collaboration Base of Precision Medicine for Cancer, Changsha 410008, China; National Clinical Research Center for Gerontology, Changsha 410008, China. Electronic address: lunquansun@csu.edu.cn. ^[6]

关键词 DNA damage repair glutamine synthetase radiation resistance