首页> Scientific reports> Comparing human iPSC-cardiomyocytes versus HEK293T cells unveils disease-causing effects of Brugada mutation A735V of Na<sub>V</sub>1.5 sodium channels.

Comparing human iPSC-cardiomyocytes versus HEK293T cells unveils disease-causing effects of Brugada mutation A735V of Na<sub>V</sub>1.5 sodium channels.

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第一作者： Jeanne,de la Roche

第一单位： Institute for Neurophysiology, Hannover Medical School, Carl-Neuberg-Str.1, 30625, Hannover, Germany. delaroche.jeanne@mh-hannover.de.

作者： Jeanne,de la Roche ^[1] ; Paweorn,Angsutararux ^[2] ; Henning,Kempf ^[3] ; Montira,Janan ^[2] ; Emiliano,Bolesani ^[4] ; Stefan,Thiemann ^[5] ; Daniel,Wojciechowski ^[5] ; Michelle,Coffee ^[4] ; Annika,Franke ^[4] ; Kristin,Schwanke ^[4] ; Andreas,Leffler ^[6] ; Sudjit,Luanpitpong ^[2] ; Surapol,Issaragrisil ^[7] ; Martin,Fischer ^[5] ; Robert,Zweigerdt ^[8]

作者单位： Institute for Neurophysiology, Hannover Medical School, Carl-Neuberg-Str.1, 30625, Hannover, Germany. delaroche.jeanne@mh-hannover.de. ^[1] Siriraj Center of Excellence for Stem Cell Research (SiSCR), Faculty of Medicine, Siriraj Hospital, 2, Bangkoknoi, Bangkok, 10700, Thailand. ^[2] Department of Cardiac, Thoracic, Transplantation and Vascular Surgery (HTTG), Leibniz Research Laboratories for Biotechnology and Artificial Organs (LEBAO) and Hans Borst Zentrum (HBZ), Hannover Medical School, Carl-Neuberg-Str.1, 30625, Hannover, Germany.;Department of Stem Cell Discovery, Novo Nordisk A/S, 2760, Maaloev, Denmark. ^[3] Department of Cardiac, Thoracic, Transplantation and Vascular Surgery (HTTG), Leibniz Research Laboratories for Biotechnology and Artificial Organs (LEBAO) and Hans Borst Zentrum (HBZ), Hannover Medical School, Carl-Neuberg-Str.1, 30625, Hannover, Germany. ^[4] Institute for Neurophysiology, Hannover Medical School, Carl-Neuberg-Str.1, 30625, Hannover, Germany. ^[5] Department of Anaesthesiology and Intensive Care, Hannover Medical School, Carl-Neuberg-Str.1, 30625, Hannover, Germany. ^[6] Siriraj Center of Excellence for Stem Cell Research (SiSCR), Faculty of Medicine, Siriraj Hospital, 2, Bangkoknoi, Bangkok, 10700, Thailand. surapol.iss@mahidol.ac.th. ^[7] Department of Cardiac, Thoracic, Transplantation and Vascular Surgery (HTTG), Leibniz Research Laboratories for Biotechnology and Artificial Organs (LEBAO) and Hans Borst Zentrum (HBZ), Hannover Medical School, Carl-Neuberg-Str.1, 30625, Hannover, Germany. zweigerdt.robert@mh-hannover.de. ^[8]