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Rapid Elimination of Broadly Neutralizing Antibodies Correlates with Treatment Failure in the Acute Phase of Simian-Human Immunodeficiency Virus Infection.

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第一作者： Yanling,Wu

第一单位： MOE/NHC/CAMS Key Laboratory of Medical Molecular Virology, School of Basic Medical Sciences, Shanghai Medical College, Fudan University, Shanghai, China yanlingwu@fudan.edu.cn tlying@fudan.edu.cn.

作者： Yanling,Wu ^[1] ; Jing,Xue ^[2] ; Chunyu,Wang ^[3] ; Wei,Li ^[4] ; Lili,Wang ^[3] ; Weizao,Chen ^[4] ; Ponraj,Prabakaran ^[5] ; Desheng,Kong ^[6] ; Yujia,Jin ^[3] ; Dan,Hu ^[3] ; Yulu,Wang ^[3] ; Cheng,Lei ^[3] ; Diao,Yu ^[7] ; Chao,Tu ^[8] ; Ariola,Bardhi ^[9] ; Igor,Sidorov ^[10] ; Liying,Ma ^[6] ; Harris,Goldstein ^[9] ; Chuan,Qin ^[2] ; Lu,Lu ^[3] ; Shibo,Jiang ^[3] ; Dimiter S,Dimitrov ^[4] ; Tianlei,Ying ^[1]

作者单位： MOE/NHC/CAMS Key Laboratory of Medical Molecular Virology, School of Basic Medical Sciences, Shanghai Medical College, Fudan University, Shanghai, China yanlingwu@fudan.edu.cn tlying@fudan.edu.cn. ^[1] Key Laboratory of Human Disease Comparative Medicine of Ministry of Health, Beijing Key Laboratory for Animal Models of Emerging and Re-emerging Infectious Diseases, Institute of Laboratory Animal Science, Chinese Academy of Medical Sciences (CAMS) and Comparative Medicine Center, Peking Union Medical College, Beijing, China. ^[2] MOE/NHC/CAMS Key Laboratory of Medical Molecular Virology, School of Basic Medical Sciences, Shanghai Medical College, Fudan University, Shanghai, China. ^[3] Protein Interactions Section, Cancer and Inflammation Program, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Frederick, Maryland, USA. ^[4] Intrexon Corporation, Germantown, Maryland, USA. ^[5] State Key Laboratory of Infectious Disease Prevention and Control, National Center for AIDS/STD Control and Prevention (NCAIDS), Chinese Center for Disease Control and Prevention, Beijing, China. ^[6] MOE/NHC/CAMS Key Laboratory of Medical Molecular Virology, School of Basic Medical Sciences, Shanghai Medical College, Fudan University, Shanghai, China.;Biomissile Corporation, Shanghai, China. ^[7] Biomissile Corporation, Shanghai, China. ^[8] Department of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, New York, USA.;Department of Pediatrics, Albert Einstein College of Medicine, Bronx, New York, USA. ^[9] Department of Medical Microbiology, Leiden University Medical Center, Leiden, The Netherlands. ^[10]

关键词 HIV-1 acute SHIV infection broadly neutralizing antibodies

医学主题词动物(Animals);抗体, 病毒(Antibodies, Viral);抗病毒药(Antiviral Agents);宿主与病原体相互作用(Host-Pathogen Interactions);猕猴(Macaca mulatta);猴获得性免疫缺陷综合征(Simian Acquired Immunodeficiency Syndrome)

DOI 10.1128/JVI.01077-19

PMID 31375583

发布时间 2020-06-08

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