Analysis of electro-mechanical relationship in human iPS cell-derived cardiomyocytes sheets under proarrhythmic condition assessed by simultaneous field potential and motion vector recordings.

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作者： Atsushi,Sugiyama ^[1] ; Mihoko,Hagiwara-Nagasawa ^[2] ; Ryuichi,Kambayashi ^[2] ; Ai,Goto ^[2] ; Koki,Chiba ^[2] ; Atsuhiko T,Naito ^[2] ; Yasunari,Kanda ^[3] ; Akio,Matsumoto ^[4] ; Hiroko,Izumi-Nakaseko ^[2]

作者单位： Department of Pharmacology, Faculty of Medicine, Toho University, 5-21-16 Omori-nishi, Ota-ku, Tokyo 143-8540, Japan; Department of Aging Pharmacology, Faculty of Medicine, Toho University, 5-21-16 Omori-nishi, Ota-ku, Tokyo 143-8540, Japan. Electronic address: atsushi.sugiyama@med.toho-u.ac.jp. ^[1] Department of Pharmacology, Faculty of Medicine, Toho University, 5-21-16 Omori-nishi, Ota-ku, Tokyo 143-8540, Japan. ^[2] Division of Pharmacology, National Institute of Health Sciences, 3-25-26 Tonomachi, Kawasaki-ku Kawasaki, Kanagawa 210-9501, Japan. ^[3] Department of Aging Pharmacology, Faculty of Medicine, Toho University, 5-21-16 Omori-nishi, Ota-ku, Tokyo 143-8540, Japan. ^[4]

关键词 Electro-mechanical relationship Human iPS cell-derived cardiomyocytes Motion vector

主题词心律失常, 心性(Arrhythmias, Cardiac);细胞分化(Cell Differentiation);细胞, 培养的(Cells, Cultured);人类(Humans);诱导多能干细胞(Induced Pluripotent Stem Cells);微电极(Microelectrodes);肌细胞, 心脏(Myocytes, Cardiac)

DOI 10.1016/j.jphs.2019.07.006

PMID 31377016

发布时间 2020-02-26

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