High Level Expression of MHC-II in HPV+ Head and Neck Cancers Suggests that Tumor Epithelial Cells Serve an Important Role as Accessory Antigen Presenting Cells.

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作者： Steven F,Gameiro ^[1] ; Farhad,Ghasemi ^[2] ; John W,Barrett ^[2] ; Anthony C,Nichols ^[2] ; Joe S,Mymryk ^[3]

作者单位： Department of Microbiology and Immunology, The University of Western Ontario, London, ON N6A 3K7, Canada. ^[1] Department of Otolaryngology, Head & Neck Surgery, The University of Western Ontario, London, ON N6A 3K7, Canada. ^[2] Department of Oncology, The University of Western Ontario, London, ON N6A 3K7, Canada. ^[3] London Regional Cancer Program, Lawson Health Research Institute, London, ON N6C 2R5, Canada. ^[4] Department of Microbiology and Immunology, The University of Western Ontario, London, ON N6A 3K7, Canada. jmymryk@uwo.ca. ^[5] Department of Otolaryngology, Head & Neck Surgery, The University of Western Ontario, London, ON N6A 3K7, Canada. jmymryk@uwo.ca. ^[6] Department of Oncology, The University of Western Ontario, London, ON N6A 3K7, Canada. jmymryk@uwo.ca. ^[7] London Regional Cancer Program, Lawson Health Research Institute, London, ON N6C 2R5, Canada. jmymryk@uwo.ca. ^[8]

关键词 MHC-II T-cell antigen presentation co-stimulatory molecules head and neck carcinoma human papillomavirus major histocompatibility complex survival signals

DOI 10.3390/cancers11081129

PMID 31394808

发布时间 2020-10-01

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