首页> Molecular diversity> Synthesis and biological evaluation of 1,2,4-triazolidine-3-thiones as potent acetylcholinesterase inhibitors: in vitro and in silico analysis through kinetics, chemoinformatics and computational approaches.

Synthesis and biological evaluation of 1,2,4-triazolidine-3-thiones as potent acetylcholinesterase inhibitors: in vitro and in silico analysis through kinetics, chemoinformatics and computational approaches.

导出 LinkOut

翻译打印收藏纠错

第一作者： Prasad G,Mahajan

第一单位： Department of Chemistry, Kongju National University, Gongju, Chungnam, 32588, Republic of Korea.

作者： Prasad G,Mahajan ^[1] ; Nilam C,Dige ^[2] ; Balasaheb D,Vanjare ^[1] ; Hussain,Raza ^[2] ; Mubashir,Hassan ^[3] ; Sung-Yum,Seo ^[4] ; Chong- Hyeak,Kim ^[5] ; Ki Hwan,Lee ^[6]

作者单位： Department of Chemistry, Kongju National University, Gongju, Chungnam, 32588, Republic of Korea. ^[1] Department of Biological Sciences, Kongju National University, Gongju, Chungnam, 32588, Republic of Korea. ^[2] Institute of Molecular Biology and Biotechnology, The University of Lahore, Defence Road, Lahore, 54590, Pakistan. ^[3] Department of Biological Sciences, Kongju National University, Gongju, Chungnam, 32588, Republic of Korea. dnalove@kongju.ac.kr. ^[4] Center for Chemical Analysis, Korea Research Institute of Chemical Technology, Yuseong, Daejeon, 34114, Republic of Korea. ^[5] Department of Chemistry, Kongju National University, Gongju, Chungnam, 32588, Republic of Korea. khlee@kongju.ac.kr. ^[6]

关键词 1,2,4-triazolidine-3-thiones Acetylcholinesterase inhibition Ionic liquid Lipinski rule Molecular docking