Calcium-Sensing Receptor Internalization Is <i>β</i>-Arrestin-Dependent and Modulated by Allosteric Ligands.
第一作者:
Iris,Mos
第一单位:
Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.
作者:
医学主题词
别构调节(Allosteric Regulation);钙(Calcium);荧光共振能量转移(Fluorescence Resonance Energy Transfer);GTP结合蛋白质α亚单位, Gi-Go(GTP-Binding Protein alpha Subunits, Gi-Go);GTP结合蛋白质α亚单位, Gq-G11(GTP-Binding Protein alpha Subunits, Gq-G11);基因敲除技术(Gene Knockout Techniques);HEK293细胞(HEK293 Cells);人类(Humans);配体(Ligands);突变(Mutation);萘类(Naphthalenes);苯乙胺类(Phenethylamines);丙胺类(Propylamines);蛋白质转运(Protein Transport);受体, 钙敏感(Receptors, Calcium-Sensing)
DOI
10.1124/mol.119.116772
PMID
31399503
发布时间
2025-02-13
- 浏览1
Molecular pharmacology
463-474页
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