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首页> Contemporary clinical trials> A randomized pragmatic trial of telephone-delivered cognitive behavioral-therapy, modafinil, and combination therapy of both for fatigue in multiple sclerosis: The design of the "COMBO-MS" trial.

A randomized pragmatic trial of telephone-delivered cognitive behavioral-therapy, modafinil, and combination therapy of both for fatigue in multiple sclerosis: The design of the "COMBO-MS" trial.

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作者： Anna L,Kratz ^[1] ; Kevin N,Alschuler ^[2] ; Dawn M,Ehde ^[2] ; Gloria,von Geldern ^[2] ; Roderick,Little ^[3] ; Shubhangi,Kulkarni ^[4] ; Kristen,Pickup ^[4] ; Tiffany J,Braley ^[5]

作者单位： Department of Physical Medicine and Rehabilitation, Michigan Medicine, University of Michigan, Ann Arbor, MI, USA. Electronic address: alkratz@med.umich.edu. ^[1] Department of Rehabilitation Medicine, University of Washington, Seattle, WA, USA. ^[2] Department of Biostatistics, University of Michigan, Ann Arbor, MI, USA. ^[3] Department of Physical Medicine and Rehabilitation, Michigan Medicine, University of Michigan, Ann Arbor, MI, USA. ^[4] Department of Neurology, Michigan Medicine, University of Michigan, Ann Arbor, MI, USA. ^[5]

关键词 Cognitive behavioral therapy Fatigue Modafinil Multiple sclerosis Patient-centered Pragmatic trial

主题词女(雌)性(Female);人类(Humans);男(雄)性(Male);中枢神经系统刺激剂(Central Nervous System Stimulants);综合疗法(Combined Modality Therapy);疲劳(Fatigue);目的(Goals);多发性硬化(Multiple Sclerosis);疾病严重程度指数(Severity of Illness Index);单盲法(Single-Blind Method);应激, 心理学(Stress, Psychological);电话(Telephone)

DOI 10.1016/j.cct.2019.105821

PMID 31400515

发布时间 2024-03-25

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