换一批
换一批Doxorubicin as a fluorescent reporter identifies novel MRP1 (ABCC1) inhibitors missed by calcein-based high content screening of anticancer agents.
作者：
关键词
ABC transporterABCC1Afatinib (PubChem CID: 10184653)Alisertib (PubChem CID: 24771867)Alvespimycin (PubChem CID: 5288674)Amuvatinib (PubChem CID: 11282283)Anti-cancer agentCelecoxib (PubChem CID: 2662)Doramapimod (PubChem CID: 156422)DoxorubicinDrug absorption and dispositionDrug profilingDrug-transporter interactionsFlavopiridol (PubChem CID: 5287969)GSK2126458 (PubChem CID: 25167777)GSK461364 (PubChem CID: 15983966)GW4064 (PubChem CID: 9893571)High content screeningLY2228820 (PubChem CID: 11570805)LY294002 (PubChem CID: 3973)MK-2206 (PubChem CID: 24964624)MRP1MRP1 inhibitorsMifepristone (PubChem CID: 55245)Multidrug resistanceNVP-BSK805 (PubChem CID: 57339395)OSI-420 (PubChem CID: 18924996)Rosiglitazone (PubChem CID: 77999)Saracatinib (PubChem CID: 10302451)
主题词
抗肿瘤药(Antineoplastic Agents);生物学鉴定法(Biological Assay);细胞系, 肿瘤(Cell Line, Tumor);多柔比星(Doxorubicin);抗药性, 肿瘤(Drug Resistance, Neoplasm);荧光素类(Fluoresceins);荧光染料(Fluorescent Dyes);HEK293细胞(HEK293 Cells);高通量筛选分析(High-Throughput Screening Assays);人类(Humans);多药耐药相关蛋白质类(Multidrug Resistance-Associated Proteins);蛋白质转运(Protein Transport);结果可重复性(Reproducibility of Results)
DOI
10.1016/j.biopha.2019.109289
PMID
31401398
发布时间
2020-02-05
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