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Canonical Wnt5b Signaling Directs Outlying Nkx2.5+ Mesoderm into Pacemaker Cardiomyocytes.

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第一作者： Jie,Ren

第一单位： Department of Medicine, Division of Cardiology, University of California, San Diego, La Jolla, CA 92093, USA.

作者： Jie,Ren ^[1] ; Peidong,Han ^[1] ; Xuanyi,Ma ^[2] ; Elie N,Farah ^[1] ; Joshua,Bloomekatz ^[3] ; Xin-Xin I,Zeng ^[4] ; Ruilin,Zhang ^[1] ; Megan M,Swim ^[1] ; Alec D,Witty ^[1] ; Hannah G,Knight ^[4] ; Rima,Deshpande ^[1] ; Weizhe,Xu ^[2] ; Deborah,Yelon ^[4] ; Shaochen,Chen ^[5] ; Neil C,Chi ^[6]

作者单位： Department of Medicine, Division of Cardiology, University of California, San Diego, La Jolla, CA 92093, USA. ^[1] Department of Bioengineering, University of California, San Diego, La Jolla, CA 92093, USA. ^[2] Department of Medicine, Division of Cardiology, University of California, San Diego, La Jolla, CA 92093, USA; Department of Biology, University of Mississippi, Oxford, MS 38677, USA. ^[3] Division of Biological Sciences, University of California, San Diego, La Jolla, CA 92093, USA. ^[4] Department of Bioengineering, University of California, San Diego, La Jolla, CA 92093, USA; Department of NanoEngineering, University of California, San Diego, La Jolla, CA 92093, USA; Institute for Engineering in Medicine, University of California, San Diego, La Jolla, CA 92093, USA. ^[5] Department of Medicine, Division of Cardiology, University of California, San Diego, La Jolla, CA 92093, USA; Institute for Engineering in Medicine, University of California, San Diego, La Jolla, CA 92093, USA; Institute of Genomic Medicine, University of California, San Diego, La Jolla, CA 92093, USA. Electronic address: nchi@ucsd.edu. ^[6]

关键词 3D bioprinting Wnt5b canonical Wnt signaling differentiation human pluripotent stem cells pacemaker cardiomyocytes zebrafish