Oligosaccharides Modulate Rotavirus-Associated Dysbiosis and TLR Gene Expression in Neonatal Rats.

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作者： Ignasi,Azagra-Boronat ^[1] ; Malén,Massot-Cladera ^[2] ; Karen,Knipping ^[1] ; Belinda,Van't Land ^[2] ; Sebastian,Tims ^[3] ; Bernd,Stahl ^[4] ; Jan,Knol ^[3] ; Johan,Garssen ^[5] ; Àngels,Franch ^[3] ; Margarida,Castell ^[3] ; Francisco J,Pérez-Cano ^[3] ; Maria J,Rodríguez-Lagunas ^[3]

作者单位： Physiology Section, Department of Biochemistry and Physiology, Faculty of Pharmacy and Food Science, University of Barcelona (UB), 08028 Barcelona, Spain. ^[1] Nutrition and Food Safety Research Institute (INSA-UB), 08921 Santa Coloma de Gramenet, Spain. ^[2] Danone Nutricia Research, 3584 CT Utrecht, The Netherlands. ^[3] Division of Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Faculty of Science, Utrecht University, 3584 CA Utrecht, The Netherlands. ^[4] University Medical Centre Utrecht/Wilhelmina Children's Hospital, Department of Pediatric Immunology, 3584 EA Utrecht, The Netherlands. ^[5] Physiology Section, Department of Biochemistry and Physiology, Faculty of Pharmacy and Food Science, University of Barcelona (UB), 08028 Barcelona, Spain. franciscoperez@ub.edu. ^[6] Nutrition and Food Safety Research Institute (INSA-UB), 08921 Santa Coloma de Gramenet, Spain. franciscoperez@ub.edu. ^[7]

关键词 HMOs TLR microbiota rotavirus scGOS/lcFOS

主题词动物(Animals);动物, 新生(Animals, Newborn);腹泻(Diarrhea);女(雌)性(Female);小肠(Intestine, Small);寡糖类(Oligosaccharides);大鼠(Rats);大鼠, 近交Lew(Rats, Inbred Lew);轮状病毒属(Rotavirus);轮状病毒感染(Rotavirus Infections);Toll样受体(Toll-Like Receptors)

DOI 10.3390/cells8080876

PMID 31405262

发布时间 2023-10-13

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Oligosaccharides Modulate Rotavirus-Associated Dysbiosis and TLR Gene Expression in Neonatal Rats.

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Oligosaccharides Modulate Rotavirus-Associated Dysbiosis and TLR Gene Expression in Neonatal Rats.

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