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Epitranscriptomic Addition of m<sup>5</sup>C to HIV-1 Transcripts Regulates Viral Gene Expression.

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第一作者： David G,Courtney

第一单位： Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, NC 27710, USA.

作者： David G,Courtney ^[1] ; Kevin,Tsai ^[1] ; Hal P,Bogerd ^[1] ; Edward M,Kennedy ^[1] ; Brittany A,Law ^[2] ; Ann,Emery ^[3] ; Ronald,Swanstrom ^[4] ; Christopher L,Holley ^[2] ; Bryan R,Cullen ^[5]

作者单位： Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, NC 27710, USA. ^[1] Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA. ^[2] Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27514, USA. ^[3] Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27514, USA; Department of Biochemistry and Biophysics, University of North Carolina at Chapel Hill, Chapel Hill, NC 27514, USA. ^[4] Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, NC 27710, USA. Electronic address: bryan.cullen@duke.edu. ^[5]

关键词 5-methyl cytosine HIV-1 NSUN2 RNA modification RNA splicing epitranscriptomic translation of mRNA