A Thpok-Directed Transcriptional Circuitry Promotes Bcl6 and Maf Expression to Orchestrate T Follicular Helper Differentiation.

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第一作者： Melanie S,Vacchio

第一单位： Laboratory of Immune Cell Biology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD, USA.

作者： Melanie S,Vacchio ^[1] ; Thomas,Ciucci ^[1] ; Yayi,Gao ^[1] ; Masashi,Watanabe ^[2] ; Mariah,Balmaceno-Criss ^[1] ; Mitchell T,McGinty ^[1] ; Allan,Huang ^[1] ; Qi,Xiao ^[1] ; Cameron,McConkey ^[1] ; Yongmei,Zhao ^[3] ; Jyoti,Shetty ^[3] ; Bao,Tran ^[3] ; Marion,Pepper ^[4] ; Golnaz,Vahedi ^[5] ; Marc K,Jenkins ^[6] ; Dorian B,McGavern ^[7] ; Rémy,Bosselut ^[8]

作者单位： Laboratory of Immune Cell Biology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD, USA. ^[1] Experimental Immunology Branch, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD, USA. ^[2] Center for Cancer Research Sequencing Facility, Advanced Technology Research Facility, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD, USA. ^[3] Department of Immunology, University of Washington, Seattle, WA, USA. ^[4] Department of Genetics, University of Pennsylvania, Philadelphia, PA, USA. ^[5] Center for Immunology, Department of Microbiology and Immunology, University of Minnesota, Minneapolis, MN, USA. ^[6] Viral Immunology and Intravital Imaging Section, National Institute of Neurological Disorders and Stroke, NIH, Bethesda, MD, USA. ^[7] Laboratory of Immune Cell Biology, Center for Cancer Research, National Cancer Institute, NIH, Bethesda, MD, USA. Electronic address: bosselur@nih.gov. ^[8]

关键词 Bcl6 CD4 T cells Maf Thpok follicular helper T cells germinal center reaction