Blood Pressure-Associated Genetic Variants in the Natriuretic Peptide Receptor 1 Gene Modulate Guanylate Cyclase Activity.

导出 LinkOut

翻译打印收藏纠错

作者： Sara,Vandenwijngaert ^[1] ; Clara D,Ledsky ^[1] ; Najim,Lahrouchi ^[2] ; Mohsin A F,Khan ^[3] ; Florian,Wunderer ^[4] ; Lisa,Ames ^[3] ; Toshiyuki,Honda ^[1] ; John L,Diener ^[5] ; Connie R,Bezzina ^[6] ; Emmanuel S,Buys ^[6] ; Donald B,Bloch ^[6] ; Christopher,Newton-Cheh ^[4] ; CHARGE+ Exome Chip Blood Pressure Consortium, the CHD Exome+ Consortium, the Exome BP Consortium, the GoT2D Consortium, the T2D-GENES Consortium and the UK Biobank CardioMetabolic Consortium BP Working Group ^[3]

作者单位： Department of Anesthesia, Critical Care, and Pain Medicine (S.V., C.D.L., F.W., E.S.B., D.B.B.), Massachusetts General Hospital Research Institute and Harvard Medical School, Boston. ^[1] Center for Genomic Medicine (N.L., C.N.-C.), Massachusetts General Hospital Research Institute and Harvard Medical School, Boston. ^[2] Department of Clinical and Experimental Cardiology, Amsterdam Cardiovascular Sciences, the Netherlands (N.L., M.A.F.K., C.R.B.). ^[3] Amsterdam UMC, University of Amsterdam, Heart Center (M.A.F.K., C.R.B.). ^[4] Department of Anesthesiology, Intensive Care Medicine and Pain Therapy, UniversityHospital Frankfurt, Germany (F.W.). ^[5] Novartis Institutes for BioMedical Research (L.A., T.H., J.L.D.). ^[6] Division of Rheumatology, Allergy and Immunology, Department of Medicine (D.B.B.), Massachusetts General Hospital Research Institute and Harvard Medical School, Boston. ^[7] Cardiovascular Research Center, Department of Medicine (C.N.-C.), Massachusetts General Hospital Research Institute and Harvard Medical School, Boston. ^[8] Program in Medical and Population Genetics, Broad Institute, Cambridge, MA (C.N.-C.). ^[9]

关键词 blood pressure cyclic GMP genetic variation natriuretic peptide vasodilation

主题词动物(Animals);血压(Blood Pressure);遗传变异(Genetic Variation);鸟苷酸环化酶(Guanylate Cyclase);人类(Humans);高血压(Hypertension);多态性, 单核苷酸(Polymorphism, Single Nucleotide);受体, 心钠素(Receptors, Atrial Natriuretic Factor)

DOI 10.1161/CIRCGEN.119.002472

PMID 31430210

发布时间 2020-07-23

翻译满意度评价：

准确一般字义偏差语意偏离译文作用小提交

浏览3

Circulation. Genomic and precision medicine

2019年12卷8期

e002472页

相似文献

中文期刊
外文期刊
学位论文
会议论文

检索历史清除

Blood Pressure-Associated Genetic Variants in the Natriuretic Peptide Receptor 1 Gene Modulate Guanylate Cyclase Activity.

Circulation. Genomic and precision medicine

相似文献

Circulation. Genomic and precision medicine

相关期刊

参考文献：
指定格式：	NoteExpress EndNote RefWorks NoteFirst

检索历史 清除

Blood Pressure-Associated Genetic Variants in the Natriuretic Peptide Receptor 1 Gene Modulate Guanylate Cyclase Activity.

Circulation. Genomic and precision medicine

相似文献

Circulation. Genomic and precision medicine

相关期刊

检索历史清除